>>9922061 (LB)
Lots of fuckery afoot, I say
Look at the dates and how quickly it changes to fear porn in today's CNN interview.
Ok, here is an article from The Langone Center Mews Media:
July 01.2020
Dr. Rapkiewicz:
Autopsies performed on those who lost their battle with 2019 coronavirus disease (COVID-19) can provide crucial information about the virus. That information is being used to help understand the disease and how to treat COVID-19.
Amy V. Rapkiewicz, MD, chair of the Department of Pathology at NYU Winthrop Hospital and director of autopsies for NYU Long Island School of Medicine, shares her observations with The Washington Post. Although it is too early to tell whether her findings will lead to new treatments, Dr. Rapkiewicz says they open up new areas of study.
Jeffrey S. Berger, MD, director of NYU Langone’s Center for the Prevention of Cardiovascular Disease, is one of the clinician–scientists taking the information discovered from autopsies and testing possible COVID-19 treatments.
Dr. Rapkiewicz’s reports suggest antiplatelet medications, like aspirin, could be helpful to stave off complications caused by COVID-19, and Dr. Berger is currently recruiting for a clinical trial to answer this question.
“It’s only one piece of a very big puzzle, and we have a lot more to learn,” Dr. Berger says. “But if we can prevent significant complications, and if more patients can survive the infection, that changes everything.”
From their website thru the Washington Post.
https://nyulangone.org/news/washington-post-coronavirus-autopsies-help-us-understand-treat-others-infected-virus
Next: July 02.2020 from the National Library of Medicine, Dr. Rapkiewicz was one of many…
Insights Into Pathogenesis of Fatal COVID-19 Pneumonia From Histopathology With Immunohistochemical and Viral RNA Studies
Jennifer L Sauter 1, Marina K Baine 1, Kelly J Butnor 2, Darren J Buonocore 1, Jason C Chang 1, Achim A Jungbluth 1, Matthias J Szabolcs 3, Sejal Morjaria 4 5, Sharon L Mount 2, Natasha Rekhtman 1, Elena Selbs 6, Zong-Mei Sheng 7, Yongli Xiao 7, David E Kleiner 8, Stefania Pittaluga 8, Jeffery K Taubenberger 7, Amy V Rapkiewicz 6, William D Travis 1
Affiliations expand
PMID: 32614086 DOI: 10.1111/his.14201
Abstract
Introduction: We describe postmortem pulmonary histopathologic findings of COVID-19 pneumonia in patients with a spectrum of disease course, from rapid demise to prolonged hospitalization.
Methods: Histopathologic findings in postmortem lung tissue from eight patients who died from COVID-19 pneumonia were reviewed. Immunohistochemistry (IHC) and next generation sequencing (NGS) were performed to detect virus.
Results: Diffuse alveolar damage (DAD) was seen in all cases with a spectrum of acute phase and/or organizing phase. IHC with monoclonal antibodies against SARS-CoV-2 viral nucleoprotein and spike protein detected virus in areas of acute but not organizing DAD, with intracellular viral antigen and RNA expression seen predominantly in patients with duration of illness less than 10 days. Major vascular findings included thrombi in medium and large caliber vessels, platelet microthrombi detected by CD61 IHC, and fibrin microthrombi.
Conclusions: Presence of SARS-CoV-2 viral RNA by NGS early in the disease course and expression of viral antigen by IHC exclusively in the acute but not in the organizing phase of DAD, suggests that the virus may play a major role in initiating the acute lung injury of DAD, but when DAD progresses to the organizing phase, the virus may have been cleared from the lung by the patient's immune response. These findings suggest the possibility of a major change during the disease course of COVID-19 pneumonia that may have therapeutic implications. Frequent thrombi and microthrombi may also present potential targets for therapeutic intervention.
Keywords: COVID-19; SARS-CoV-2; diffuse alveolar damage; immunohistochemistry; lung histopathology; next generation sequencing; thrombi; viral pneumonia.
https://pubmed.ncbi.nlm.nih.gov/32614086/