Endogenous Deficiency of Glutathione as the Most Likely Cause of Serious Manifestations and Death in COVID-19 Patients

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7263077/

Abstract

Higher rates of serious illness and death from coronavirus SARS-CoV-2 (COVID-19) infection among older people and those who have comorbidities suggest that age- and disease-related biological processes make such individuals more sensitive to environmental stress factors including infectious agents like coronavirus SARS-CoV-2. Specifically, impaired redox homeostasis and associated oxidative stress appear to be important biological processes that may account for increased individual susceptibility to diverse environmental insults. The aim of this Viewpoint is to justify (1) the crucial roles of glutathione in determining individual responsiveness to COVID-19 infection and disease pathogenesis and (2) the feasibility of using glutathione as a means for the treatment and prevention of COVID-19 illness. The hypothesis that glutathione deficiency is the most plausible explanation for serious manifestation and death in COVID-19 patients was proposed on the basis of an exhaustive literature analysis and observations. The hypothesis unravels the mysteries of epidemiological data on the risk factors determining serious manifestations of COVID-19 infection and the high risk of death and opens real opportunities for effective treatment and prevention of the disease.

I believe this is saying that deficiencies in the diet are the reason that some people die from Coronavirus. That would mean that we can prevent the disease simply by eating the right foods in the run-up to cold and flu season.

>>9948057

N-Acetylcysteine: A Potential Therapeutic Agent for SARS-CoV-2

https://pubmed.ncbi.nlm.nih.gov/32504923/

Abstract

COVID-19, a respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to spread across the globe. Predisposing factors such as age, diabetes, cardiovascular disease, and lowered immune function increase the risk of disease severity. T cell exhaustion, high viral load, and high levels of TNF-ɑ, IL1β, IL6, IL10 have been associated with severe SARS-CoV-2. Cytokine and antigen overstimulation are potentially responsible for poor humoral response to the virus. Lower cellular redox status, which leads to pro-inflammatory states mediated by TNF-ɑ is also potentially implicated. In vivo, in vitro, and human clinical trials have demonstrated N-acetylcysteine (NAC) as an effective method of improving redox status, especially when under oxidative stress. In human clinical trials, NAC has been used to replenish glutathione stores and increase the proliferative response of T cells. NAC has also been shown to inhibit the NLRP3 inflammasome pathway (IL1β and IL18) in vitro, and decrease plasma TNF-ɑ in human clinical trials. Mediation of the viral load could occur through NAC's ability to increase cellular redox status via maximizing the rate limiting step of glutathione synthesis, and thereby potentially decreasing the effects of virally induced oxidative stress and cell death. We hypothesize that NAC could act as a potential therapeutic agent in the treatment of COVID-19 through a variety of potential mechanisms, including increasing glutathione, improving T cell response, and modulating inflammation. In this article, we present evidence to support the use of NAC as a potential therapeutic agent in the treatment of COVID-19.

Yet another treatment for COVID that is available over the counter. Personally I would add this to the combo of Zinc and either strong green tea or Quercetin. That means NAC + Zinc + an ionophore. Of course you could use HCQ for the ionophore if you can get it. And don't forget to boost your Vitamin D and Vitamin C consumption, and to use NSAIDs. Taking a cold and flu prep with Acetaminophen should be fine, but if you are hard hit, add Ibuprofen as well.

9/11 in Roman numerals IX, XI

What does it all meanSome people went to a lot of trouble to figure out number patterns in the observed world and how they interrelate, then recorded all this information in a dense symbolic manner and adjusted ancient Akkadian tales to fit these numeric patterns. And this was likely done over a period of centuries at minimum.

>>9948198

Rain is when the WATER comes drip, drip, dropping down from the SKY.

This SKY EVENT often starts small with occasional DROPS

And then picks up the pace, after few thunderous BOOMs

Until it is a veritable STORM of DROPS falling left and right

Creating a FLOOD of BIBLICAL proportions.

But remember…

Symbolism will be their downfall!

Well that is what raindrops do, isn't it?

The water drops DOWNFALL

But if this is symbolic, then we are not talking about H2O

What rhymes with H2O….. hmmm….

I know… INFO

The RAIN is not DROPS of H2O

Instead is a storm of unveiled INFO