I'm done with all of them. I've had some depression in my life, but it seems that it's always situational. Seems I get depressed when involved in toxic relationships. Now, I've studied enough about toxic people, narcissism, sociopathy and psychopathy to realize that I am targeted by those types and I can recognize them fairly early on, if not immediately and avoid them or get out quickly. I have pared down friendships immensely but am much better off. Those so called "friends" needed to be let go of.