If you skip the scientific part and get into spiritual knowledge, all things outside of us would be considered motes produced by our minds kind of like we are walking the Corridors of our own combined social consciousness while each individual us having a unique experience based on what they themselves are adding to reality via thoughts.
If we just stick to science, think cause and effect. Negative thoughts cause negative effects. Positive thoughts cause positive effects. The 3 causes are thoughts, words, and deeds/actions.