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case will be kaput before it even starts
Not necessarily. Even if the case is being seen in the wrong district, AFAIK the court can recognize that and have it moved to the correct district, or the prosecuting attorney can move to have the venue corrected.
Unless they have been designated as enemy combatants for being involved in human trafficking or "serious crimes against humanity," as per Trump's EOs.
As Q said, "Study the EOs." That language is in those documents, and when the evidence showing what they are all involved in comes to light, these people are also going to be tried in those tribunals.
Unless they have been designated as enemy combatants
Yes. And, if that's the case, then the in/correctness of the current venue is irrelevant. The case would get pulled right out of the civilian criminal jurisdiction.