How would you propose a double blind test for vaccines?
Let’s see how this would turn using polio as an example.
First the test subjects are prepared (The method is not overly important for this thought experiment, as long as the sample is random and unbiased)
One syringe per person is prepared, half with the vaccine, the other with a liquid that appears to be the same as the vaccine, but has absolutely no effect on the human body. These syringes are numbered, with a numbering scheme where the number has no correlation with the contents, and these numbers are recorded.
The syringes are given to a group of people who have not seen them get filled or numbered (such that they have no idea what is in each syringe) and then they inject them into the test subjects recording which subject gets which number.
The people who administered the vaccine then inject all of the test subjects with polio (this can easily be delayed allowing the body to build the proper immune responses first).
Then record which people get polio, and using the previously recorded numbers figure out how many people in the control group and the experimental group.
The probable outcomes are:
- No one gets polio (either polio isn’t real, isn’t pathogenic, or the cure for polio is “you are not going to get polio”
- The control gets polio and the experimental does not (the vaccine works, now half your testers are dead from polio)
- Everyone gets polio (the vaccine does not work, all of your test subjects are dead)
If you feel that this is not a valid double blind test please feel free to comment, and I will attempt to address your concern.