HCQ inhibits HIV?
2003:
Effects of chloroquine on viral infections: an old drug against today’s diseases
Effects on HIV infection, Anti-HIV effects of chloroquine
"The anti-HIV activity of chloroquine has been shown not only in cell line models, but also in peripheral blood lymphocytes and monocytes —ie, cell culture models in which cellular uptake of chloroquine is closer to the conditions occurring in vivo. Under these conditions, it was possible to obtain levels of inhibition of viral replication above 90%."
DOI:https://doi.org/10.1016/S1473-3099(03)00806-5
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(03)00806-5/fulltext
https://archive.vn/cTZGM
''(I found a bunch of HCQ <HIV studies)''
1996:
Inhibition of HIV-1 replication by hydroxychloroquine: mechanism of action and comparison with zidovudine
"HCQ suppressed HIV-1 replication in a dose-dependent manner in both recently and chronically infected T-cell and monocytic cell lines."
https://www.clinicaltherapeutics.com/article/S0149-2918(96)80063-4/fulltext
https://archive.vn/LK3QV
1993:
Inhibition of Human Immunodeficiency Virus Type 1 Replication by Hydroxychloroquine in T Cells and Monocytes
"These data suggest that HCQ may be useful adjunctive therapy in the treatment of HIV-1 infection."
https://pubmed.ncbi.nlm.nih.gov/8427717/?dopt=Abstract
https://archive.vn/06fWY
1995:
Hydroxychloroquine Treatment of Patients With Human Immunodeficiency Virus Type 1
"The amount of recoverable HIV-1 RNA in plasma declined significantly in the HCQ group over the 8-week period (P = 0.022), while it increased in the placebo group."
https://pubmed.ncbi.nlm.nih.gov/8565026/?dopt=Abstract
https://archive.vn/18UXF
https://archive.vn/M8iZr
1996:
The Antiinflammatory and Antiviral Effects of Hydroxychloroquine in Two Patients With Acquired Immunodeficiency Syndrome and Active Inflammatory Arthritis
"HCQ may exert simultaneous anti-inflammatory and antiviral effects in patients with HIV infection and inflammatory arthritis. If larger studies confirm this observation, it may be the drug of choice in this population of patients."
https://pubmed.ncbi.nlm.nih.gov/8546725/?dopt=Abstract
https://archive.vn/Dyfy0
2004:
Chloroquine and Hydroxychloroquine as Inhibitors of Human Immunodeficiency Virus (HIV-1) Activity
"Chloroquine and its analog hydroxychloroquine are two inexpensive agents that are widely used for the treatment of malaria and have been shown to achieve some level of anti-HIV activity."
https://pubmed.ncbi.nlm.nih.gov/15320751/
https://archive.vn/AskWC
2001:
The anti-HIV-1 activity of chloroquine.
"Interestingly, CQ is capable of inhibiting HIV-1 replication at concentrations within the range reported in plasma of individuals chronically treated with doses of the drug which have well-known and limited toxicity."
https://pubmed.ncbi.nlm.nih.gov/11166661/
https://archive.vn/aXgYF
2002:
Hydroxychloroquine, hydroxycarbamide, and didanosine as economic treatment for HIV-1
"This new combination of drugs could be suitable for countries that have restricted resources"
https://pubmed.ncbi.nlm.nih.gov/12020529/
https://archive.vn/Ne1jY
2005:
Hydroxychloroquine, hydroxyurea and didanosine as initial therapy for HIV-infected patients with low viral load: safety, efficacy and resistance profile after 144 weeks
"This novel and well-tolerated combination controls viral replication during long-term follow up, with development of few resistance mutations. With careful monitoring it may be a useful strategy for delaying highly active antiretroviral therapy (HAART) and associated toxicity in selected patients with low initial viral loads."
https://pubmed.ncbi.nlm.nih.gov/15670247/
https://archive.vn/76fxQ
Small sampling of studies
Imagine if HCQ was widely prescribed and suddenly HIV positive people began testing HIV negative.