Maybe more exoskeleton type stuff. Getting a dude in a mechanical frame that can carry a ton of weight is a fine way to load him up with thicker heavy duty armor, probably a decently big gun too if the suit has some sort of stabilization thing going on.
The biggest challenges would be the power supply, making the wearer/pilot doesn't overheat or otherwise be at risk from the suit's function, designing the actual suit to be good armor (I don't think making thicker plate would work here), and of course the helmet. Last one is actually a pretty big one, a few ways around it from just leaving it as the weak link with a glass or other transparent visor to look out of it to adding a camera and screen to it. VR can potentially help with this, maybe even giving the user wider field of vision. Though that has the problem of power consumption and sensitive electronics which might be damaged by gunfire.
Another problem is just space. Like a dude's legs are only so wide apart, you can't really armor the inside that much without making movement a pain. Plus each suit would need to be adjustable or custom to one user.
So it's plausible, not really practical but it could be done given some work.
More realistically I'd figure we'll get mechs first. Not the bipedal ones, as great as it sounds to have a walking mech wheels or treads are usually fine. So really they'd basically be a tank with arms instead of a cannon, smaller ones but still they could have more versatile applications, carry some good guns, and still have the finesse for fine tasks. I'm not sure how useful this would be, but on the engineering side it's easier.