>>14765080

>molnupiravir

Molnupiravir Antiviral Description

Molnupiravir (MK-4482, EIDD-2801) is an experimental oral antiviral developed initially to treat influenza at Emory University. Molnupiravir is an orally bioavailable form of a potent ribonucleoside analog that inhibits replicating multiple RNA viruses, including SARS-CoV-2, the causative agent of COVID-19.

Molnupiravir (MK-4482) consists of the nucleoside analog N4-hydroxycytidine. Molnupiravir has been evaluated against coronaviruses, including SARS-1, MERS-CoV. In addition, Molnupiravir is active in several models of SARS-CoV-2, including for prophylaxis, treatment, and prevention of transmission.

Miami, Florida-based Ridgeback Biotherapeutics L.P., and its partner Merck, conducted a comprehensive nonclinical program to characterize the safety profile of molnupiravir, including assays such asBig Blue and PIG-a,which are designed to provide a robust measure of a drug or chemical's ability to induce mutations in vivo. In addition, animals were administered molnupiravir for more extended and higher doses (mg/Kg) than those employed in human studies. These studies' totality indicates that molnupiravir is not mutagenic or genotoxic in vivo mammalian systems.

The Phase 3 portion of the global MOVe-OUT trial studying molnupiravir in non-hospitalized adult patients with laboratory-confirmed COVID-19 and at least one risk factor associated with poor disease outcomes is underway. In addition, Merck plans to initiate a clinical program to evaluate molnupiravir for post-exposure prophylaxis in the second half of 2021.

"These data are promising, and we are pleased to be able to present the Phase 2 interim results for molnupiravir while we proceed with the Phase 3 portion of MOVe-OUT in non-hospitalized patients," said Wendy Holman, CEO, Ridgeback Biotherapeutics, in a press statement issued on Jul 12, 2021. "There remains a great need for a range of solutions for the pandemic, and we are hopeful that molnupiravir will play a role in helping patients."

"As the (COVID-19) pandemic continues to evolve and surges are being reported in many places around the world, it is important that we investigate new ways to protect individuals exposed to the (SARS-CoV-2) virus from becoming infected with symptomatic disease," said Dr. Nick Kartsonis, SVP, vaccines, and infectious diseases, clinical research, Merck Research Laboratories, in a press statement issued on September 1, 2021.

The MOVe-AHEAD study is a Phase 3 multicenter, randomized, double-blind, placebo-controlled clinical trial evaluating the efficacy and safety of orally administered molnupiravir compared to placebo in preventing the spread of SARS-CoV-2, the virus that causes COVID-19, within households. Last updated on October 1, 2021.

Merck confirmed plans on October 1, 2021, to seek Emergency Use Authorization in the U.S.and regulatory agencies worldwide. If Authorized, Molnupiravir could be the first oral antiviral medicine for COVID-19.

more bs

https://www.precisionvaccinations.com/vaccines/molnupiravir-antiviral

Guess we're getting up to the CGI, Deepfake drops.

60 Minutes' reporter gets the deepfake treatment as he explores the potentially dangerous technology

On Sunday’s edition of 60 Minutes, journalist Bill Whitaker went deep into the world of deepfakes and synthetic media, where artificial intelligence is used to make images and videos that are fake but look hyper-realistic.

Whitaker had a deepfake video made that aged him back 30 years, and even had the ability to take away his mustache. He also had a synthetic avatar made of himself that was able to speak words he never actually spoke, only typed into a computer, exactly as he would say them.

While deepfakes can be used for fun, like the popular Tom Cruise deepfakes on TikTok, Whitaker spoke to one of the first people to write a book on the topic, Nina Schick, who called the technology a “game changer” when it comes to disinformation. Especially due to how fast it is evolving.

“By five to seven years, we are basically looking at a trajectory where any single creator, so, a YouTuber, a TikToker, will be able to create the same level of visual effects that is only accessible to the most well-resourced Hollywood studio today,” Schick said.

Whitaker pointed out that most deepfakes are protected free speech, and that legislation has been all over the map in different parts of the country. The problem is, not only is the government trying to keep up with the rapidly improving technology, the general public as a whole is still very much in the dark about what this technology is, and what it’s capable of.

Some viewers took to Twitter with reactions ranging from “mind blown” to being “reawakened” to issuing an even more stern warning about how potentially dangerous this could be.

https://www.yahoo.com/entertainment/60-minutes-reporter-gets-the-deepfake-treatment-as-he-explores-the-potentially-dangerous-technology-070211434.html

>>14765162

> rally on Tuesday March 12

?

Typo's and shit

>>14765244

>Regular gas is $4.06 a gallon.

Welcome to CA 2018

>>14765417

We control nothing. Just let it all go.

Had high momentum years ago, got lots of new eyes on the movement, and that's about it.

Now it's up to those "Elected Heavy Lifters".

Nothing we do will matter at this point. They have the script. We never understood Comms. THEY all did, because it's a big ass club, blah, blah. But, we were needed, just on a "need to know" basis.

It's always easy to tell people to hang on, when you're privy of the game moves…

However, they forget about the walking a mile in someone else's shoes.

Illusion or not, is all fucked up.

>>14765506

>I’d like to know…maybe we will in a few years. Of course i may not be here

Collateral Damage. Just numbers. These controllers are sick. sigh