>>14878719 (lb)
>No, the really hideous news, it appears, is that it is basically universal that the jabs produce OAS in every single person who takes them and thus you will not only get Covid, you'll get it more than once if you were stupid enough to take the shot(s).
>>14878889 (lb)
Moar…
Excerpt:
The Wages of Original Antigenic Sin
Absorption studies, in which various viruses were used to selectively remove serum antibodies, suggested that repeat exposures to dominant antigens of first-infecting viruses, when seen later as lesser or secondary antigens on subsequently infecting viruses, somehow reinforced antibody responses to the original strains at the apparent expense of responses to newer strains (4). Francis announced “the doctrine of original antigenic sin” (5,6): “[t]he antibody-forming mechanisms appear to be oriented by the initial infections of childhood so that exposures later in life to antigenically related strains result in a progressive reinforcement of the primary antibody” (3). Later studies by many investigators showed original antigenic sin to be a general phenomenon associated with numerous related/sequentially infecting virus strains that contain multiple external epitopes of varying cross-specificity (i.e., ability to elicit cross-reactive antibody), including antigenically drifting viruses such as influenza A, and the more stable flaviviruses, which circulate concurrently as multiple distinct viruses, virus serotypes, and virus strains (7,8).
Original antigenic sin seems to be most pronounced when sequential viruses are of intermediate antigenic relatedness; when they are antigenically complex; and when sequential exposure intervals are long, consistent with ongoing selection and expansion of lymphocyte clones that have increasing antibody avidity at key cross-reactive epitopes (7–10) and possibly with epitope competition between naïve and antigen-specific B cells (8). A phenomenon analogous to original antigenic sin also has been described with cytotoxic T lymphocytes (11). Although conclusive evidence in humans is lacking, original antigenic sin recently has come under scrutiny as a possible cause of viral immune escape, enhanced disease severity, decreased efficacy of influenza vaccines (8,12–14), and increased incidence of influenza in 2009 after vaccination with a related virus in 2008–2009 (15). On a positive note, original antigenic sin has also been linked to vaccine-induction of heterosubtypic neutralizing antibodies (16).
https://wwwnc.cdc.gov/eid/article/16/6/10-0453_article