Anonymous ID: 53b712 Nov. 13, 2021, 12:15 p.m. No.14991913   🗄️.is 🔗kun   >>2036

So if you do a search on "quinine +boron", you get this NIH article about the first enantioselective boron-tethered Diels-Alder reaction using quinine as a chiral promoter, in 2018.

 

https://pubmed.ncbi.nlm.nih.gov/29715015/

 

All Greek to me, so I go look up Enantioselective synthesis-

the synthesis of a compound by a method that favors the formation of a specific enantiomer or diastereomer. Enantiomers are stereoisomers that have opposite configurations at every chiral center. Diastereomers are stereoisomers that differ at one or more chiral centers.

 

Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity.

 

Still all Greek to me, but I know to "think mirror".

Perhaps a chemistry/physiology anon could shed light on how this fits in the puzzle?

 

https://en.m.wikipedia.org/wiki/Enantioselective_synthesis