Anonymous ID: 27916e Aug. 15, 2022, 4:28 a.m. No.17397144   🗄️.is 🔗kun

https://www.nature.com/articles/s42255-022-00609-6

Systemic induction of senescence in young mice after single heterochronic blood exchange

Ageing is the largest risk factor for many chronic diseases. Studies of heterochronic parabiosis, substantiated by blood exchange and old plasma dilution, show that old-age-related factors are systemically propagated and have pro-geronic effects in young mice. However, the underlying mechanisms how bloodborne factors promote ageing remain largely unknown. Here, using heterochronic blood exchange in male mice, we show that aged mouse blood induces cell and tissue senescence in young animals after one single exchange. This induction of senescence is abrogated if old animals are treated with senolytic drugs before blood exchange, therefore attenuating the pro-geronic influence of old blood on young mice. Hence, cellular senescence is neither simply a response to stress and damage that increases with age, nor a chronological cell-intrinsic phenomenon. Instead, senescence quickly and robustly spreads to young mice from old blood. Clearing senescence cells that accumulate with age rejuvenates old circulating blood and improves the health of multiple tissues.

Anonymous ID: 27916e Aug. 15, 2022, 4:37 a.m. No.17397162   🗄️.is 🔗kun   >>7174

https://thelincolnite.co.uk/2022/08/overnight-road-closures-for-over-three-months-on-a17-between-beckingham-and-leadenham/

Overnight road closures for over three months on A17 between Beckingham and Leadenham

Works to reconstruct the section of A17 between Beckingham and Leadenham will start on Monday, September 12.

The total programme of works is expected to last for up to three and half months, subject to weather. There will likely be a break in the works during the Christmas period.

As part of the scheme, the A17 between Sleaford Road in Beckingham to Leadenham Low Fields, will be closed overnight from 7pm to 6am, weekday nights only.

Please note that some weekend working will be required from 7pm Friday night until 6am on the following Monday morning. The proposed weekends are September 30 to October 3; 7-10 October 7-10; and October 14-17.

Anonymous ID: 27916e Aug. 15, 2022, 4:39 a.m. No.17397168   🗄️.is 🔗kun

https://www.macrumors.com/2022/08/04/apple-chip-supplier-hit-by-intel-delay/

Apple Chip Supplier Hit by Intel Delay Ahead of 'A17 Bionic' Production in 2023

Apple is believed to be the main customer of TSMC's initial 3nm chip mass production. According to the report, Apple is now the only major company among the first wave of 3nm chip production clients with orders scheduled between the second half of 2022 and the start of 2023. Apple's upcoming 3nm chips reportedly include new M-series chips and the "A17 Bionic."

Anonymous ID: 27916e Aug. 15, 2022, 4:54 a.m. No.17397203   🗄️.is 🔗kun   >>7226 >>7329

https://www.justice.gov/opa/video/attorney-general-merrick-garland-delivers-remarks-announcing-motion-unseal-search-warrant

Attorney General Merrick Garland Delivers Remarks Announcing Motion to Unseal Search Warrant

Anonymous ID: 27916e Aug. 15, 2022, 5 a.m. No.17397223   🗄️.is 🔗kun   >>7231

https://www.nbcnews.com/politics/justice-department/justice-department-sues-idaho-abortion-ban-first-post-roe-litigation-rcna41174

Justice Department sues Idaho over abortion ban in first post-Roe litigation

Attorney General Garland has repeatedly said the Department of Justice "is going to use every tool we have to ensure reproductive freedom" and was reviewing its options.

Anonymous ID: 27916e Aug. 15, 2022, 5:05 a.m. No.17397234   🗄️.is 🔗kun   >>7269

https://www.mprnews.org/story/2022/08/15/npr-why-scientists-have-pumped-a-potent-greenhouse-gas-into-streams-on-public-lands

Why scientists have pumped a potent greenhouse gas into streams on public lands

Blacktail Deer Creek in Yellowstone National Park, seen here in a 2019 photo from the ecological study known as NEON, is one site where researchers have bubbled sulfur hexafluoride into the water.

A massive ecological study that's happening across the United States, and which is designed to track the impact of long-term changes like a warming climate, is deliberately releasing a highly potent and persistent greenhouse gas in national parks and forests.

The gas, sulfur hexafluoride, is "the most potent greenhouse gas known to date," according to the Environmental Protection Agency. It's 22,800 times more effective at trapping heat than carbon dioxide, and lasts in the atmosphere for thousands of years.

So far, this ecology study has released around 108 pounds of the gas, which has about the same impact as burning more than a million pounds of coal.

That may not seem like a big deal in the grand scheme of global emissions, but government scientists working at federal parks and forests have objected to using this gas on public lands — especially since this major study is designed to go on for 30 years and alternative gasses are available.

This kerfuffle has so far played out quietly within government agencies. But it comes at a time when all kinds of researchers are thinking about the climate effects of past practices, with some saying that scientists who understand the urgency of the climate crisis have a special obligation to set an example to the public by reducing the greenhouse gas emissions of their own work.

The National Science Foundation (NSF), which funds this large ecology study, told NPR that it supports an evaluation that's now underway to see whether phasing out the use of this gas would affect the quality of the information that's being gathered.

That's not good enough for one watchdog group, which is calling for an immediate halt to the release of this gas on public lands.

Anonymous ID: 27916e Aug. 15, 2022, 5:09 a.m. No.17397246   🗄️.is 🔗kun

>>17397241

>https://en.wikipedia.org/wiki/Robby_Mook

https://www.cbsnews.com/news/hillary-clinton-durham-investigation-robby-mook/

Former Clinton campaign manager Robby Mook says Clinton agreed to give Trump-Russia material to reporter

Robby Mook, the former campaign manager for Hillary Clinton, testified on Friday that the 2020 Democratic presidential nominee agreed to provide information about a link between her opponent Donald Trump and Russian Alfa Bank to a reporter, despite the fact that her campaign was not certain about the truth of the allegations.

During cross examination, Mook said the campaign was not fully confident in the Alfa Bank allegations and wanted to give them to a reporter so the reporter could "run it down further" and verify it.

Slate first published a story suggesting Alfa Bank, a Moscow-based financial institution, had a server that was "irregularly pinging" a server registered to the New York-based Trump Organization. The FBI investigated, and a report by the Justice Department inspector general said it concluded that there were no links between Alfa Bank and Trump.

Mook took the stand during the trial of Michael Sussmann who is charged in special counsel John Durham's probe with lying to the FBI during the Trump-Russia investigation after he brought the FBI unverified evidence concerning Trump and Alfa Bank. The scope of the trial is narrow, focusing on whether or not Sussmann, whose law firm represented Clinton's 2016 presidential campaign, was acting on behalf of a client.

Mook said the decision to release the Alfa allegations to a reporter was discussed with senior campaign officials, including senior policy adviser and now the White House national security adviser, Jake Sullivan; campaign chairman John Podesta and communications director Jennifer Palmieri.

Clinton was briefed about the decision to go to the press with the allegations in the fall of 2016, and according to Mook, "she thought we made the right decision."

Mook testified he did not see the Alfa allegations as a "silver bullet" that would end the Trump campaign, referring to other information being published linking Trump to Russia.

Slate's article on the purported link between Alfa Bank and Trump ran on Oct. 31, 2016, days before Election Day. When asked by prosecutor Andrew DeFilippis if he doubted the credibility of the allegations when the article ran, Mook said he was "not a cyber expert' and thought that the article gave the claims more credibility.

"I'm sure you know reporters publish things that aren't true," DeFilippis pushed back.

Mook testified that going to the FBI did not seem like "an effective way" of getting the information to the public. He said the campaign didn't trust the FBI, noting, "Two of probably the most damaging days to the campaign were caused by James Comey, not by Donald Trump."

When asked if Clinton approved of Sussman going to the FBI, Mook said he was not aware, "I don't know why she would have."

Mook testified it was "malpractice" not to conduct opposition research, detailing that opposition research on Trump was very complicated. "He was incredibly litigious, so there was a lot of work to be done around different lawsuits that he filed or had been filed against him." Sussmann's law firm Perkins Coie played a role in this work, according to Mook.

In his second day of testimony, then-FBI general counsel James Baker told the jury that had he learned Sussman, whose law firm represented Clinton's 2016 presidential campaign, had billed his time to the Clinton campaign for drafting papers presented to the FBI, he would "absolutely" have been concerned. This was tied to the central question of the trial — whether Sussmann had brought the information to investigators on his own and not on behalf of any legal client.

Had Baker known who Sussmann's clients were, he said he would have feared the FBI was being pulled into a political ploy. "I would have had serious conversations with the leadership of the FBI about what if anything to do with this material and how to handle it."

This is the first criminal trial stemming from the Durham investigation.