Anonymous ID: 7922f7 Jan. 25, 2023, 7:44 p.m. No.18227441   🗄️.is đź”—kun   >>7644 >>7880 >>7941 >>7953

>>18227432

https://en.wikipedia.org/wiki/Directed_evolution

Directed evolution (DE) is a method used in protein engineering that mimics the process of natural selection to steer proteins or nucleic acids toward a user-defined goal. It consists of subjecting a gene to iterative rounds of mutagenesis (creating a library of variants), selection (expressing those variants and isolating members with the desired function) and amplification (generating a template for the next round). It can be performed in vivo (in living organisms), or in vitro (in cells or free in solution). Directed evolution is used both for protein engineering as an alternative to rationally designing modified proteins, as well as for experimental evolution studies of fundamental evolutionary principles in a controlled, laboratory environment.

Anonymous ID: 7922f7 Jan. 25, 2023, 7:46 p.m. No.18227456   🗄️.is đź”—kun

https://www.wcvb.com/article/duxbury-massachusetts-summer-street-crime-scene/42645654

Mother to be charged in deaths of two children found unconscious in Duxbury, Massachusetts home, DA says

A 32-year-old mother will be charged with murder in the death of her two children, the Plymouth County District Attorney announced on Wednesday.

Two children, ages 5 and under, died and a 7-month-old boy was flown to a Boston area hospital with traumatic injuries, after being discovered inside the family's Duxbury, Massachusetts, home on Tuesday night.

District Attorney Tim Cruz identified the mother as Lindsay Clancy. He said that it appeared the children were strangled.

"As soon as able, we will be arraigning her on the two charges of murder in the death of her children," Cruz said. Cruz would not say where in the home the children were discovered.

Cruz said an arrest warrant was been issued Wednesday night for Clancy for two counts of homicide and three counts each of strangulation and assault and battery with a deadly weapon for the deaths of 5-year-old Cora Clancy and 3-year-old Dawson Clancy.

According to the DA, first responders discovered the three children unconscious inside the home with obvious signs of trauma.

First responders rushed to the home at 47 Summer St. in Duxbury just after 6 p.m. Tuesday after receiving a 911 call from Clancy's husband.

Cruz said the man reported the attempted suicide of Clancy, who had jumped out of a window in the home.

Cruz said Wesley Clancy, a 7-month-old, was being treated at a Boston hospital. An update on his condition was not available.

Cruz said the chief medical examiner's office will ultimately determine the manner and means of the death of the children.

"This is an unimaginable, senseless tragedy, and it is an ongoing investigation," Cruz said.

Cruz said Clancy was treated at the scene and transported to an area hospital for treatment, where she remained on Wednesday afternoon. An update on her condition was not immediately available.

Authorities would not comment on whether any mental illness may have played a role in the homicides or if there was any mental health history.

A spokesperson for Massachusetts General Hospital confirmed Clancy is an employee.

"We are shocked and saddened to learn of this unthinkable tragedy," the hospital spokesperson wrote. "We extend our deepest sympathies to all those affected by these devastating events."

Two relatives of the family stopped by the home Wednesday, bringing flowers and leaving them at the end of the driveway. Both were very emotional and in tears, saying they are struggling to understand what happened.

"They were just beautiful, beautiful children," Donna Jesse said. "They had a beautiful life. I can't – I can't process it."

Neighbors in the small community are in shock and thinking of the family.

"It's sort of like, how can this happen around here? But it's just you put yourself in, like you said, the man’s place and can’t imagine how devastating that is," Duxbury resident Tom McGrath said.

"This is an isolated incident, and there is no further threat to the community," Duxbury police chief Michael Carbone said.

"Duxbury police detectives, along with the state police detectives that are working nonstop and will continue in the days, weeks, months, or whatever it takes to get answers," Carbone said.

Anonymous ID: 7922f7 Jan. 25, 2023, 7:48 p.m. No.18227471   🗄️.is đź”—kun   >>7493

https://www.wcvb.com/article/man-arrested-no-clothes-covered-crash-plaistow-police-nh/42665314

Man arrested wearing no clothes, covered in blood after crash in New Hampshire

PLAISTOW, N.H. — A New Hampshire man is facing multiple charges after he ran away from the scene of a Plaistow crash while naked, according to police.

Timothy O'Rourke, of Danville, was arrested Wednesday morning and charged with driving while intoxicated, resisting arrest, conduct after an accident, two counts of indecent exposure and two counts of simple assault.

Plaistow police said they received reports shortly after 8:50 a.m. of a three-car crash with injury near the intersection of Plaistow Road (Route 125) and Main Street (Route 121A).

Responding officers found multiple vehicles with heavy damage at the scene, but no serious injuries were reported in the crash.

Those officers were told by witnesses that the driver of a black Jeep Compass, later identified as O'Rourke, caused the crash and fled on foot down Main Street.

Police said they were able to find O'Rourke within minutes and said he was running behind Main Street homes wearing no clothes and coated in his own blood.

O'Rourke is expected to be arraigned Feb. 6 in Salem District Court.

Anonymous ID: 7922f7 Jan. 25, 2023, 7:51 p.m. No.18227499   🗄️.is đź”—kun   >>7644 >>7880 >>7941 >>7953

https://www.wcvb.com/article/paul-pelosi-attack-footage-to-be-released/42665246

Paul Pelosi attack footage to be released, California judge orders

Footage of the attack on former U.S. House Speaker Nancy Pelosi's husband will be released to the public after a judge on Wednesday denied prosecutors' request to keep it secret.

San Francisco Superior Court Judge Stephen M. Murphy ruled there was no reason to keep the footage secret, especially after prosecutors played it in open court during a preliminary hearing last month, according to Thomas R. Burke, a San Francisco-based lawyer who represented The Associated Press and a host of other news agencies in their attempt to access the evidence.

The San Francisco District Attorney's Office handed over the evidence to Murphy on Wednesday following a court hearing. Murphy asked the court clerk's office to distribute it to the media, which could happen as soon as Thursday.

Paul Pelosi, Nancy Pelosi's husband, was asleep at the couple's San Francisco home on Oct. 28 when someone broke in and beat him with a hammer. Prosecutors have charged 42-year-old David DePape in connection with the attack.

During a preliminary hearing last month, prosecutors played portions of Paul Pelosi's 911 call plus footage from Capitol police surveillance cameras, body cameras worn by the two police officers who arrived at the house, and video from DePape's interview with police.

But when news organizations asked for copies of that evidence, the San Francisco District Attorney's Office refused to release it. The attack, which occurred just days before the 2022 midterm elections, prompted intense speculation from the public that fueled the spread of false information.

The district attorney's office argued releasing the footage publicly would only allow people to manipulate it in their quest to spread false information.

But the news agencies argued it was vital for prosecutors to publicly share their evidence that could debunk any false information swirling on the internet about the attack.

"You don't eliminate the public right of access just because of concerns about conspiracy theories," Burke said.

The San Francisco District Attorney's Office did not respond to an email from The Associated Press seeking comment.

The news agencies who sought the release of the footage includes The New York Times, The Washington Post, the Los Angeles Times, the San Francisco Chronicle, The Press Democrat, CNN, Fox News, CBS, ABC, NBC and KQED, an NPR-member radio station in San Francisco.

DePape pleaded not guilty last month to six charges, including attempted murder. Police have said DePape told them there was "evil in Washington" and he wanted to harm Nancy Pelosi because she was second in line to the presidency. His case is pending.

Democrats lost their majority in the House of Representatives after the midterm elections. Republicans elected California Republican U.S. Rep. Kevin McCarthy as the new speaker. Pelosi will remain in Congress, but she stepped down as Democratic leader. She was replaced by Hakeem Jeffries from New York.

Anonymous ID: 7922f7 Jan. 25, 2023, 8:23 p.m. No.18227703   🗄️.is đź”—kun   >>7710

In January 2009, Weber essentially ended his company’s dealings with Theranos—he confirmed with Theranos that Pfizer had paid what it owed as part of a $900,000 exploratory deal. After that, he said, he was not aware of any further “meaningful” interactions between the two companies.

Anonymous ID: 7922f7 Jan. 25, 2023, 8:24 p.m. No.18227710   🗄️.is đź”—kun

>>18227703

Mary Anne Rhyne, a spokeswoman for GSK told us that "GSK has not done any business with Theranos in the past two years." When we asked if the company had worked with Theranos before then, she told us that she didn't "have more information to share." A Theranos spokesperson told us that Theranos had engaged in clinical trial testing for GSK starting in 2008, however, but that was before Theranos opened its retail business.

 

Pfizer, on the other hand, told the Financial Times that the company's dealings with Theranos were limited. "We've done only very limited historical exploratory work with Theranos through a few pilot projects," the Pfizer representative said, "and we do not have any current or active projects with them."