TURBO CANCER Literature is growing rapidly - 6 new COVID-19 Vaccine Turbo Cancer papers published in April 2024 - 26 total

https://makismd.substack.com/p/turbo-cancer-literature-is-growing

TURBO CANCER LITERATURE (15 papers/preprints):

(2024 Apr, Zhang and El-Deiry) - SARS-CoV-2 spike S2 subunit inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells

https://www.biorxiv.org/content/10.1101/2024.04.12.589252v1

(2024 Apr, Rubio-Casillas et al) - Review: N1-methyl-pseudouridine (m1Ψ): Friend or foe of cancer?

https://pubmed.ncbi.nlm.nih.gov/38583833/

(2024 Apr, Gibo et al) - Increased Age-Adjusted Cancer Mortality After the Third mRNA-Lipid Nanoparticle Vaccine Dose During the COVID-19 Pandemic in Japan

https://www.cureus.com/articles/196275-increased-age-adjusted-cancer-mortality-after-the-third-mrna-lipid-nanoparticle-vaccine-dose-during-the-covid-19-pandemic-in-japan#!/

(2023 Dec, Angues et al) - SARS-CoV-2 Vaccination and the Multi-Hit Hypothesis of Oncogenesis

https://pubmed.ncbi.nlm.nih.gov/38234925/

(2023 Nov, Patrick Chambers) - The CD147 Epitope on SARS CoV2 and the Spike in Cancer, Autoimmunity and Organ Fibrosis

https://www.researchgate.net/publication/375312458_The_CD147_Epitope_on_SARS_CoV2_and_the_Spike_in_Cancer_Autoimmunity_and_Organ_Fibrosis/fulltext/65465084b1398a779d5b0a1d/The-CD147-Epitope-on-SARS-CoV2-and-the-Spike-in-Cancer-Autoimmunity-and-Organ-Fibrosis.pdf

(2023 Oct, Speicher et al) - DNA fragments detected in monovalent and bivalent Pfizer/BioNTech and Moderna modRNA COVID-19 vaccines from Ontario, Canada: Exploratory dose response relationship with serious adverse events.

https://osf.io/xv3nz/

(2023 Sep, McKernan et al) - Sequencing of bivalent Moderna and Pfizer mRNA vaccines reveals nanogram to microgram quantities of expression vector dsDNA per dose

https://www.researchgate.net/publication/369967228_Sequencing_of_bivalent_Moderna_and_Pfizer_mRNA_vaccines_reveals_nanogram_to_microgram_quantities_of_expression_vector_dsDNA_per_dose

(2023 May, Uversky, Redwan, Makis, Rubio-Casillas) - IgG4 Antibodies Induced by Repeated Vaccination May Generate Immune Tolerance to the SARS-CoV-2 Spike Protein

https://pubmed.ncbi.nlm.nih.gov/37243095/

(2023 May, Eens et al) - B-cell lymphoblastic lymphoma following intravenous BNT162b2 mRNA booster in a BALB/c mouse: A case report

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183601/

(2023 Apr, Halma, Rose, Lawrie) - The Novelty of mRNA Viral Vaccines and Potential Harms: A Scoping Review

https://www.mdpi.com/2571-8800/6/2/17

(2023 March, Guetzkow et al) - National Academies Committee on Review of Relevant Literature Regarding Adverse Events Associated with Vaccines

https://nationalcitizensinquiry.b-cdn.net/wp-content/uploads/2023/09/VT-3tt-Makis-Wiseman-06b-Turbo-Cancer-Paper16-Wiseman.pdf

(2022 May, Jiang et al) - SARS–CoV–2 Spike Impairs DNA Damage Repair and Inhibits V(D)J Recombination In Vitro (Retracted)

https://pubmed.ncbi.nlm.nih.gov/34696485/

(2022 Apr, Seneff et al) - Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

https://pubmed.ncbi.nlm.nih.gov/35436552/

(2022 Feb, Alden et al) - Intracellular Reverse Transcription of Pfizer BioNTech COVID-19 mRNA Vaccine BNT162b2 In Vitro in Human Liver Cell Line

https://pubmed.ncbi.nlm.nih.gov/35723296/

(2020 Oct, Singh) - S2 Subunit of SARS-nCoV-2 Interacts with Tumor Suppressor Protein p53 and BRCA: an In Silico Study

https://pubmed.ncbi.nlm.nih.gov/32619819/

p1

>>20741795

TURBO CANCER CASES (11 papers):

===

(2024 Apr, Abdurrahman et al) - Primary Cutaneous Adenoid Cystic Carcinoma in a Rare Location With an Immune Response to a BNT162b2 Vaccine

https://pubmed.ncbi.nlm.nih.gov/38608126/

(2024 Apr, Ueda et al) - Fetal hemophagocytic lymphohistiocytosis with intravascular large B-cell lymphoma following coronavirus disease 2019 vaccination in a patient with systemic lupus erythematosus: an intertwined case

https://pubmed.ncbi.nlm.nih.gov/38619098/

(2024 Apr, Gentilini et al) - A Case Report of Acute Lymphoblastic Leukaemia (ALL)/Lymphoblastic Lymphoma (LBL) Following the Second Dose of Comirnaty®: An Analysis of the Potential Pathogenic Mechanism Based on of the Existing Literature

https://www.scienceopen.com/document?vid=90c33e63-5123-4b10-8af1-dfa006d84909

(2023 Sep, Kyriakopoulos et al) - Bell’s palsy or an aggressive infiltrating basaloid carcinoma post-mRNA vaccination for COVID-19? A case report and review of the literature

https://pubmed.ncbi.nlm.nih.gov/37927346/

(2023 Apr, Tachita et al) - Newly diagnosed extranodal NK/T-cell lymphoma, nasal type, at the injected left arm after BNT162b2 mRNA COVID-19 vaccination

https://pubmed.ncbi.nlm.nih.gov/37093551/

(2023 Jan, Cavanna et al) - Non-Hodgkin Lymphoma Developed Shortly after mRNA COVID-19 Vaccination: Report of a Case and Review of the Literature

https://pubmed.ncbi.nlm.nih.gov/36676781/

(2022 Sep, Revenga-Porcel et al) - 76M lymphoma after 3rd Moderna mRNA

https://onlinelibrary.wiley.com/doi/10.1111/jdv.18615

(2022 Aug, Sekizawa et al) - 80F lymphoma after 2nd Pfizer mRNA

https://pubmed.ncbi.nlm.nih.gov/35979213/

(2022 Jun, Zamfir et al) - 58F 2nd Pfizer, 53M 2nd Pfizer both lymphoma

https://pubmed.ncbi.nlm.nih.gov/35888593/

(2022 Apr, Mitsui et al) - 67M 2nd Pfizer, 80F 2nd Pfizer both lymphoma

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9114986/

(2021 Nov, Goldman et al) - 66M lymphoma progression after 3rd Pfizer mRNA

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8656165/

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https://twitter.com/HerdImmunity12/status/1780721201276453355

Herd Immunity News🇬🇧🇺🇸

@HerdImmunity12

Breaking: Tony Blair To Replace Klaus Schwab At WEF: During our interview with Independent UK MP

@ABridgen

this evening - he revealed that war criminal Tony Blair is likely to replace the elderly and riddled Klaus Schwab as #WEF crime boss.

The horrifying but logical step for the demonic #traitorclass.

https://twitter.com/HerdImmunity12/status/1780658703739261318

5:13 PM · Apr 17, 2024

Finland's Bold New Firearm Policy Sets Global Standard

Finland is taking a bold step forward in national defense and public safety with its groundbreaking initiative to open 300 new shooting ranges across the country. This extensive project not only aims to enhance military readiness and civilian preparedness but also integrates responsible gun ownership into the fabric of Finnish society. As geopolitical tensions rise, Finland’s proactive strategy sets a global standard for empowering citizens while fortifying national security.

The Finnish government has embarked on a significant project to open 300 new shooting ranges across the country. This initiative is part of a broader national security strategy aimed at enhancing military preparedness and public safety. By increasing access to shooting ranges, the government seeks to improve civilian readiness for national defense.

Finland’s decision to expand its shooting ranges comes amidst growing geopolitical tensions in the region, especially due to concerns about Russian military activities. As Finland shares a long border with Russia, the enhancement of civilian and military readiness is seen as a crucial step. The new shooting ranges are intended to bolster the nation’s defensive capabilities by facilitating more extensive training opportunities.

https://www.msn.com/en-us/news/world/finland-s-bold-new-firearm-policy-sets-global-standard/ss-BB1lNEKx

World Health Organization’s ‘Global Governance’ Gambit Is A Threat To Democracy

https://thefederalist.com/2024/04/18/the-world-health-organizations-global-governance-gambit-is-a-threat-to-democracy/

The World Health Assembly is set to vote on giving WHO the sole ability to determine public health emergencies and the global response.

The left loves to call any person or policy they disagree with a “threat to democracy.” Put aside the fact the United States is not a democracy but a constitutional and federal republic. The biggest threats to our form of government — and one being pushed by the Biden administration and largely ignored by Congress — are the upcoming votes on two World Health Organization (WHO) instruments that violate our representative system.

Each element of our constitutional system is at risk if the White House and Congress fail to stop the WHO’s global governance scheme.

The instruments under consideration by the WHO are amendments to the International Health Regulations (IHR) and the concurrent Pandemic Treaty, both of which will be voted on by the World Health Assembly (made up of the 196 member states) in less than two months. The purpose of these documents is to give the WHO director-general the sole ability not only to declare public health emergencies of international concern (PHEIC) but to mandate for every nation the global response such as lockdowns, travel restrictions, mandatory testing and vaccinations, and border closures. In addition, nations will be forced to spend billions of dollars to implement this global governance framework based on the principle of “equity.”

First, this is a threat to our constitutional republic because it removes the people’s elected representatives from their decision-making roles. Our elected officials on the local, state, and federal level will no longer control when and what is considered a public health emergency or what the government response will be.

The director general will have the sole authority to make declarations not only for actual pandemics but for any issue that has the potential to affect global health. Think climate change, gun violence, food security, abortion laws, rules for transgender medical interventions, and any other so-called threat to public health. The WHO has already weighed in on the “global health risks” tied to each of these hot-button political issues. There will be no ability for citizens to vote for or against the decision-makers, undermining the very concept of representative democracy.

In addition, these documents are a threat to the constitutional protections we now enjoy. The establishment of a global surveillance state by the WHO threatens the basic privacy rights of all Americans while the requirement in these accords for nations to “combat false, misleading, misinformation or disinformation” could easily violate our First Amendment freedom of speech. Each nation will be required to share intellectual property for use by other countries, decimating our unique American patent rights. Our constitutional protections will be undermined if the WHO gets its way.

Finally, under our federal system, the regulation of health care is under the purview of the states, including regulating the licensure of doctors, pharmacies, and hospitals and determining what vaccinations are required for school attendance. We experienced this clearly during the Covid crisis, when state and local leaders had, for the most part, the ability to decide when and how businesses and schools would reopen. Under the Pandemic Treaty and accompanying IHR amendments, this authority will be stripped from the states and given to an international organization in clear violation of the 10th Amendment to the Constitution.

To add insult to the very real injury about to befall us is the fact that the White House plans to sign onto the Pandemic Treaty and IHR amendments by “executive agreement” rather than submit them to the Senate for its constitutionally mandated advice and consent. And the U.S. Senate appears willing to accept this usurpation of their power. Last March, Sen. Ron Johnson, R-Wis., offered an amendment to require a Senate vote on the Pandemic Treaty, but it failed to gain even one Democrat vote. This dereliction of duty on behalf of the Senate should not be excused.

Is there a “threat to democracy” facing our country today? Yes, indeed. It is the threat to our very constitutional republic by the World Health Organization via its proposed Pandemic Treaties and the refusal of the administration and Senate to do anything to stop it. This threat is not rhetorical but very real. And we, as Americans, must unite against it.

This article was originally published at Eagle Forum.

Kristen A. Ullman is the President of Eagle Forum and a steering committee member of the Sovereignty Coalition.

Moderna 2020 patent US10703789B2: Nanobots That Release Toxins and Harvest Energy From the Body

https://patents.google.com/patent/US10703789B2/en

SUMMARY OF THE INVENTION

Described herein are compositions, methods, processes, kits and devices for the design, preparation, manufacture and/or formulation of modified mRNA (mmRNA) molecules.

The details of various embodiments of the invention are set forth in the description below. Other features, objects, and advantages of the invention will be apparent from the description and the drawings, and from the claims.

Self-Assembled Nanoparticles

Nucleic Acid Self-Assembled Nanoparticles

Self-assembled nanoparticles have a well-defined size which may be precisely controlled as the nucleic acid strands may be easily reprogrammable. For example, the optimal particle size for a cancer-targeting nanodelivery carrier is 20-100 nm as a diameter greater than 20 nm avoids renal clearance and enhances delivery to certain tumors through enhanced permeability and retention effect. Using self-assembled nucleic acid nanoparticles a single uniform population in size and shape having a precisely controlled spatial orientation and density of cancer-targeting ligands for enhanced delivery. As a non-limiting example, oligonucleotide nanoparticles were prepared using programmable self-assembly of short DNA fragments and therapeutic siRNAs. These nanoparticles are molecularly identical with controllable particle size and target ligand location and density. The DNA fragments and siRNAs self-assembled into a one-step reaction to generate DNA/siRNA tetrahedral nanoparticles for targeted in vivo delivery. (Lee et al., Nature Nanotechnology 2012 7:389-393; herein incorporated by reference in its entirety).

In one embodiment, the polynucleotides, primary constructs and/or mmRNA disclosed herein may be formulated as self-assembled nanoparticles. As a non-limiting example, nucleic acids may be used to make nanoparticles which may be used in a delivery system for the polynucleotides, primary constructs and/or mmRNA of the present invention (See e.g., International Pub. No. WO2012125987; herein incorporated by reference in its entirety).

Cell-Penetrating Polypeptides

The primary constructs or mmRNA disclosed herein, may encode one or more cell-penetrating polypeptides. As used herein, “cell-penetrating polypeptide” or CPP refers to a polypeptide which may facilitate the cellular uptake of molecules. A cell-penetrating polypeptide of the present invention may contain one or more detectable labels. The polypeptides may be partially labeled or completely labeled throughout. The polynucleotide, primary construct or mmRNA may encode the detectable label completely, partially or not at all. The cell-penetrating peptide may also include a signal sequence. As used herein, a “signal sequence” refers to a sequence of amino acid residues bound at the amino terminus of a nascent protein during protein translation. The signal sequence may be used to signal the secretion of the cell-penetrating polypeptide.

In one embodiment, the polynucleotides, primary constructs or mmRNA may also encode a fusion protein. The fusion protein may be created by operably linking a charged protein to a therapeutic protein. As used herein, “operably linked” refers to the therapeutic protein and the charged protein being connected in such a way to permit the expression of the complex when introduced into the cell. As used herein, “charged protein” refers to a protein that carries a positive, negative or overall neutral electrical charge. Preferably, therapeutic protein may be covalently linked to the charged protein in the formation of the fusion protein. The ratio of surface charge to total or surface amino acids may be approximately 0.1, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8 or 0.9.

The cell-penetrating polypeptide encoded by the polynucleotides, primary constructs or mmRNA may form a complex after being translated. The complex may comprise a charged protein linked, e.g. covalently linked, to the cell-penetrating polypeptide. “Therapeutic protein” refers to a protein that, when administered to a cell has a therapeutic, diagnostic, and/or prophylactic effect and/or elicits a desired biological and/or pharmacological effect.

p1

>>20741812

In one embodiment, the cell-penetrating polypeptide may comprise a first domain and a second domain. The first domain may comprise a supercharged polypeptide. The second domain may comprise a protein-binding partner. As used herein, “protein-binding partner” includes, but is not limited to, antibodies and functional fragments thereof, scaffold proteins, or peptides. The cell-penetrating polypeptide may further comprise an intracellular binding partner for the protein-binding partner. The cell-penetrating polypeptide may be capable of being secreted from a cell where the polynucleotide, primary construct or mmRNA may be introduced. The cell-penetrating polypeptide may also be capable of penetrating the first cell.

In a further embodiment, the cell-penetrating polypeptide is capable of penetrating a second cell. The second cell may be from the same area as the first cell, or it may be from a different area. The area may include, but is not limited to, tissues and organs. The second cell may also be proximal or distal to the first cell.

In another embodiment, the polynucleotides, primary constructs, or the mmRNA may be encapsulated into a lipid nanoparticle or a rapidly eliminated lipid nanoparticle and the lipid nanoparticles or a rapidly eliminated lipid nanoparticle may then be encapsulated into a polymer, hydrogel and/or surgical sealant described herein and/or known in the art. As a non-limiting example, the polymer, hydrogel or surgical sealant may be PLGA, ethylene vinyl acetate (EVAc), poloxamer, GELSITE® (Nanotherapeutics, Inc. Alachua, Fla.), HYLENEX® (Halozyme Therapeutics, San Diego Calif.), surgical sealants such as fibrinogen polymers (Ethicon Inc. Cornelia, Ga.), TISSELL® (Baxter International, Inc Deerfield, Ill.), PEG-based sealants, and COSEAL® (Baxter International, Inc Deerfield, Ill.).

In another embodiment, the lipid nanoparticle may be encapsulated into any polymer known in the art which may form a gel when injected into a subject. As another non-limiting example, the lipid nanoparticle may be encapsulated into a polymer matrix which may be biodegradable.

In one embodiment, the polynucleotide, primary construct, or mmRNA formulation for controlled release and/or targeted delivery may also include at least one controlled release coating. Controlled release coatings include, but are not limited to, OPADRY®, polyvinylpyrrolidone/vinyl acetate copolymer, polyvinylpyrrolidone, hydroxypropyl methylcellulose, hydroxypropyl cellulose, hydroxyethyl cellulose, EUDRAGIT RL®, EUDRAGIT RS® and cellulose derivatives such as ethylcellulose aqueous dispersions (AQUACOAT® and SURELEASE®).

In one embodiment, the controlled release and/or targeted delivery formulation may comprise at least one degradable polyester which may contain polycationic side chains. Degradeable polyesters include, but are not limited to, poly(serine ester), poly(L-lactide-co-L-lysine), poly(4-hydroxy-L-proline ester), and combinations thereof. In another embodiment, the degradable polyesters may include a PEG conjugation to form a PEGylated polymer…

MUCH more in the 248 pages (!!!) of patent docs…

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**(Not medical advice:)

All of these mrna weapons use PEG or PEG-based sealant ingredients. One might consider adding PEG (polyethylene glycol) to your 'medical records 'known allergies'. PEG is in skin creams, cosmetics, toothpaste, body cleansers, eyedrops, etc, so claiming a past exposure and an adverse event is not hard or at all suspicious.

>>20741817

>>20741812

https://twitter.com/gregreese/status/1780872580947190014

>>20741825

>the only way is the military

Yes, DARPA. DARPA contracted Moderna and Pfizer at least as early as 2013 to make the mrna gene editing nanoweapons. No other way to have done it.

A Radical Experiment Shows Cloud Brightening May Be Our Climate’s White Knight or Geo engineering goes mainstream

With a strategic spray of aerosols, scientists are working on a lofty solution to a warming world.

full frame of the abstract background with colorful clouds on a pink background

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us?

Humans are not doing a great job lowering carbon emissions, so scientists are searching for ways to buy the world time to kick its nasty fossil fuel habit.

One idea is marine cloud brightening (MCB), and a new study says that MCB could also create cloud cover, making it an even better ‘painkiller’ for climate change that previously thought.

However, there’s a lot scientists still don’t know about MCB, including how it could affect ocean circulation patterns and rainfall on land.

Coming as a surprise to no one, 2023 was the warmest year on record. And that’s just another step in an already disturbing trend that sparked the creation of the Paris Climate Accord in 2015. There’s just one problem: the world is falling behind its emission-reducing commitments.

The world is currently on track for 4.8 degrees Celsius warming by the end of the century, which is far above the 2.7 degree Celsius goal. To realize that less-apocalyptic goal, the world needs to cut 28 percent of the greenhouse gas emissions that it’s currently on track to produce, according to NPR. It’s undeniable that the world is in a bit of a time crunch, so some scientists are pursuing a Plan B—solar geoengineering. If successful, it could buy humanity time to fully kick our addiction to fossil fuels and embrace the green energy revolution.

Now, a new study by scientists at the University of Birmingham (in collaboration with other U.S. and European universities) discovered that one of these geoengineering techniques—a technology known as marine cloud brightening (MCB)—could be a more effective “painkiller” for climate change than previously realized. The researchers created a “natural experiment” by closely analyzing cloud behavior as related to the periodic eruptions of Mount Kilauea volcano in Hawaii.

These natural injections of aerosols into the atmosphere mimic the overall goal of marine cloud brightening, which (in simple terms) also injects aerosols—in the case of MCB, hyperfine sea salt particles—into clouds to increase their brightness and reflectiveness. However, the team found that MCB actually gets most of its cooling effect from creating cloud cover. The results were published in the journal Nature Geoscience on Thursday.

“Our findings show that marine cloud brightening could be more effective as a climate intervention than climate models have suggested previously,” University of Birmingham’s Ying Chen, the study’s lead author, said in a press statement. “We must continue to improve fundamental understanding of aerosol’s impacts on clouds, further research on global impacts and risks of MCB, and search for ways to decarbonize human activities.”

Using machine learning to pore over historical satellite and meteorological data, the team created a predictor that showed cloud behavior during inactive volcano periods. Then, the researchers could easily identify how the volcano directly impacted clouds. Turns out, natural aerosols increased cloud cover by 50 percent during volcanic activity, with a cooling effect of -10 watts per square meter (negative is a good thing).

“Our findings suggest that MCB may be quite effective for alleviating climate warming, although it would probably manifest as an increase in cloud cover rather than cloud opacity, as the MCB terminology implies,” the paper reads. “This best practice would be particularly effective in tropical oceans where incoming solar radiation is strong and background environment is clean (that is, clouds are more ‘pristine’).”

However, any kind of climate tool under the tech umbrella of “geoengineering” will draw some suspicion. Scientists, for example, aren’t sure how MCB could affect ocean circulation patterns, or if it could increase rainfall in some places while reducing it in others. But proponents emphasize that the world is already being geoengineered by human-created greenhouse gasses, and that the side effects of MCB could potentially be preferable to the the devastating costs of climate change.

There is one area of agreement between both camps—MCB isn’t a solution to climate change—but evidence is growing that it could be one way to lower the planet’s symptomatic fever while we attempt to treat the carbon-induced disease.

https://www.popularmechanics.com/science/environment/a60475104/marine-cloud-brightening-cloud-engineering/

>>20741839

Yet unable to stop them? So…

>>20741296

it is a mace

>>20741729

anti-viral

anti-bacterial

anti-parasitic

properties

thus why SILVERware, and golden goblets, etc

Lot if parasites etc in flesh and blood

>>20742030

>>20742047

whois?