SNL mocks Hegseth, Trump as it returns with 51st season premiere

"SNL" wasted no time before taking on the Jimmy Kimmel controversy in its season premiere.

The sketch show's cold open on Oct. 4 addressed the recent suspension of "Jimmy Kimmel Live!" and spoofed the idea that "Saturday Night Live" could be President Donald Trump's next target.

Trump (played by James Austin Johnson) popped up in the opening sketch to warn he is "keeping my eye" on the show and "making sure they don't do anything too mean about me." He went on to declare that "SNL" "better be on their best behavior, otherwise they'll have to answer to my attack dog at the FCC." Mikey Day then entered as Federal Communications Commission Chairman Brendan Carr as the song "Somebody’s Watching Me" played.

The cold open starred Jost in a rare sketch appearance as Defense Secretary Pete Hegseth delivering a speech to the nation's top generals. Jost portrayed Hegseth as stiff and full of rage as he demanded that members of the military lose weight. "Our military will now have the same rules as any good frat party: no fat chicks," he yelled.

"We are facing the greatest threat to freedom and democracy the world has ever known, and we all know what that threat is," he said, before Johnson's Trump interrupted to declare, "Late-night TV!"

https://www.usatoday.com/story/entertainment/tv/2025/10/05/snl-cold-open-season-premiere-kimmel-hegseth/86534856007/

The Nobel Prize in medicine goes to 3 scientists for work on the human immune system

STOCKHOLM (AP) — Three scientists won the Nobel Prize in medicine Monday for discoveries about how the immune system knows to attack germs and not our own bodies.

The work by Mary E. Brunkow, Fred Ramsdell and Dr. Shimon Sakaguchi uncovered a key pathway the body uses to keep the immune system in check, called peripheral immune tolerance. Experts called the findings critical to understanding autoimmune diseases such as Type 1 diabetes, rheumatoid arthritis and lupus.

In separate projects over several years, the trio of scientists — two in the U.S. and one in Japan — identified the importance of what are now called regulatory T cells. Scientists are currently using those findings in a variety of ways: to discover better treatments for autoimmune diseases, to improve organ transplant success and to enhance the body’s own fight against cancer, among others.

“Their discoveries have been decisive for our understanding of how the immune system functions and why we do not all develop serious autoimmune diseases,” said Olle Kämpe, chair of the Nobel Committee.

more…

https://apnews.com/article/nobel-prize-medicine-a68cf8a3b930570630168a949d277cde