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O7 anniversary
AI Overview
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AI-Directed E
volution: Redefining the Boundaries of Protein …
Directed evolution is a laboratory method that mimics natural selection to create biomolecules with desired traits by using iterative rounds of mutagenesis
(random mutation), selection (screening for improved traits), and amplification. This process is used in protein engineering to develop enzymes for applications like biofuel or pharmaceutical production, or to create other functional biomolecules for use in research, medicine, and industry. The key difference from natural evolution is that directed evolution achieves results much more quickly, in a few rounds of the iterative process.
How directed evolution works
Start with a gene: The process begins with a gene that encodes a specific protein or nucleic acid.
Create diversity: The gene is subjected to random mutagenesis to create a library of mutant genes, which leads to a collection of proteins with different properties.
Screen for function: The resulting variants are screened or selected for a desired function, such as increased catalytic activity, improved binding, or enhanced stability.
Repeat the process: The "winning" mutants with the improved properties are used as the starting material for the next round of diversification and screening. This iterative process allows for the accumulation of beneficial mutations over multiple rounds until the desired goal is reached.
THIS is the LINK joining TRANS and tran-sisters>
"VOA trans Pakistan" likely refers to reporting by
Voice of America (VOA) on transgender issues in Pakistan, particularly the groundbreaking 2018 Transgender Persons (Protection of Rights) Act. This act allows transgender individuals to self-identify their gender, receive recognition on official documents, and be free from discrimination in areas like employment and healthcare. VOA has also reported on other transgender rights advancements in the country, such as the selection of Pakistan's first transgender news anchor and the participation of transgender individuals in the 2018 elections.