Anonymous ID: 3a4162 May 30, 2026, 11:42 a.m. No.24661137   🗄️.is 🔗kun

Ukraine ‘deliberately’ struck Europe’s largest nuclear plant – Rosatom

 

It is the first time nuclear power plant key equipment has ever been purposely targeted, Rosatom CEO Aleksey Likhachev has said

 

The Ukrainian military attacked Russia’s Zaporozhye Nuclear Power Plant (ZNPP), puncturing a hole in the machine hall of one of the facility’s units, Aleksey Likhachev, CEO of the Russian state nuclear corporation Rosatom, has said.

 

The ZNPP – which has repeatedly been attacked by Kiev forces over the past years – came under a new attack on Saturday, with a fiber-optics-guided drone making it to the machine hall of the sixth power unit of the plant. Given that such munitions are guided by their operators until the impact, the strike was carried out deliberately, and any “theories of an accidental hit” can be ruled out, Likhachev stated.

 

“One could, if I may put it this way, ‘congratulate’ the entire international community – this is the first-ever deliberate attack on the nuclear power plant’s main equipment, with a penetrative explosion and damage to the machine hall,” he said.

 

The Ukrainian armed forces repeatedly cross not just red lines, but the very boundaries of common sense. What to expect next? Strikes directly on the turbine? The reactor hall? The reactor and its safety systems?

 

Russia has repeatedly drawn the attention of the international community to the “extremely dangerous behavior” on Kiev’s part, the nuclear chief added. Many appear not to take the continuing attacks on the ZNPP “seriously,” while a potential nuclear incident at the plant could spread well beyond Russia and Ukraine, affecting those believing themselves to be “completely safe,” Likhachev warned.

 

Radiation levels remain normal at the site, the ZNPP said in a statement. The attack caused no casualties or “critical damage” to the facility, it added. Emergency teams are currently accessing the damage sustained by the machine hall, with the situation remaining under “full control,” the ZNPP stressed.

 

In recent weeks, the Ukrainian military has ramped up attacks on the plant, repeatedly striking structures within its perimeter and targeting the facility’s employees. The ZNPP came under Moscow’s control early in the conflict and has been operated by Rosatom after the Zaporozhye Region voted to join Russia in a referendum in the fall of 2022.

 

https://www.rt.com/russia/640766-zaporozhye-nuclear-power-plant-attack/

Anonymous ID: 3a4162 May 30, 2026, 11:42 a.m. No.24661139   🗄️.is 🔗kun

Summary

Iran is pushing forward legislation formalizing control/management of Hormuz Strait shipping, which flies in the face of Trump warnings & conditions.

An Iranian Fateh-110 short-range ballistic missile targeted Kuwait's Ali Al Salem Air Base, a key operational hub for the U.S. Air Force. BBG says missile intercepted, but falling debris struck part of the base, injuring five Americans.

Two more American drones reported destroyed or damaged in the Kuwait base attack (DropSite/BBG).

Iran says two big MOU agreement issues remain & are not finalized: Unfreezing of Assets & Sanctions, Nuclear File

Anonymous ID: 3a4162 May 30, 2026, 11:46 a.m. No.24661150   🗄️.is 🔗kun

US Military Hasn't Identified A Single Confirmed Mine In Strait Of Hormuz, Officials Tell NBC

 

Just a few hours after President Trump boasted that the US Navy had detonated "numerous" Iranian sea mines, NBC News reported that, even after three months of warfare, the US military has yet to confirm the presence of even a single mine in the strategically critical Strait of Hormuz.

 

Citing two US officials and a "person familiar with the matter," NBC said relentless searches of the waterway by aerial and undersea drones haven't found any confirmed mines, merely finding some objects that might be mines. “If anything, the threat has been far less robust than we had feared,” the person "familiar with the matter" told NBC.

 

Around the time Trump decided to join Israel in launching a war on Iran in the midst of ongoing negotiations in which Tehran had offered major concessions along the lines of what Trump is demanding today, US intelligence officials believed Iran had placed mines on the south side of the strait ahead of the shooting or shortly thereafter, said NBC. Allies had likewise reportedly concluded that Iran had deployed sea mines. The mine menace was said to be so formidable that, in April, a Pentagon official speaking to US legislators in a classified session said that fully clearing the strait of mines could take six months.

 

In a Friday morning social media post in which he foreshadowed a potential ceasefire agreement that would end restrictions on commerce through the Strait of Hormuz, Trump boasted that the US Navy had "removed, through detonation, numerous such mines with our great underwater mine sweepers."

 

The NBC report seemingly contradicts multiple CBS News reports. Most recently, on May 19, the outlet reported that US intelligence had identified "at least 10 mines" in the strait. Back in March CBS reported that an official said there were at least a dozen, while another one said fewer than a dozen. CBS attributed this information to officials who weren't named.

 

The potential presence of mines has weighed heavily on the minds of ship owners and more importantly shipping-insurance underwriters who've terminated existing coverage and offered new protection at prohibitively expensive rates. Of course, mines aren't the only weapon at Iran's disposal: drones and missiles can wreak havoc as well.

 

Last week, there were reports that the UK Royal Navy was making moves for a potential deployment of hundreds of sailors on a mine-sweeping mission in the strait. However, as we emphasized, AP reported that this potential deployment would only proceed if a peace agreement were reached, suggesting it's principally a gesture meant to placate Trump, who has pestered NATO allies to help remedy the massive, strait-centered economic disruption caused by the US-Israeli decision to launch a war on Iran over a nuclear weapon program that almost certainly does not exist.

 

In March, Trump ranted against nations that were anxious over the shutting of a waterway that transports about 20% of the world's petroleum, in addition to about a third of international fertilizer trade: "Go to the strait and just take it. You have to start learning how to fight for yourself. Go get your own oil." Days later, he said, “The United States imports almost no oil through the Hormuz Strait and won’t be taking any in the future. We don’t need it. We haven’t needed it and we don’t need it.”

 

https://www.zerohedge.com/geopolitical/us-military-hasnt-identified-single-confirmed-mine-strait-hormuz-officials-tell-nbc

Anonymous ID: 3a4162 May 30, 2026, 11:50 a.m. No.24661157   🗄️.is 🔗kun   >>1167 >>1254 >>1351 >>1451 >>1619 >>1670 >>1706

Moscow Signs Military Partnership With Taliban In Full Circle Since CIA's Operation Cyclone

 

Russia and Afghanistan Discuss Regional Security and Military Cooperation.

 

The Russian Ministry of Defense announced that Deputy Defense Minister of the Russian Federation, Vasily Osmakov, met with Afghanistan's Defense Minister, .

 

The deal was concluded during the International Security Forum held in Moscow this week.

 

According to the report by Interfax’s correspondent, Taliban Defense Minister Mullah Mohammad Yaqoob held talks with Secretary of Russia's Security Council Sergei Shoigu on the sidelines of the event.

 

During the meeting, Yaqoob said that engagement with Russia is important for the Taliban-led administration and that both sides have been expanding their bilateral relations.

 

He added that Afghanistan and Russia share historic ties and that Kabul aims to maintain and strengthen those relations.

 

Shoigu urged western countries to release Afghanistan’s frozen assets and take responsibility for the country’s reconstruction during the event.

 

“We are convinced that western countries must unfreeze frozen Afghan assets, fully acknowledge their full responsibility for their 20-year presence in Afghanistan, and assume the entire burden of post-conflict reconstruction of the country,” Shoigu said.

 

One day later, on 28 May, Russia’s Deputy Defense Minister Vasily Osmakov met with Yaqoob in Moscow to discuss regional security and potential bilateral military cooperation.

 

According to the ministry, the two sides addressed security issues in Central and South Asia, as well as the outlook for cooperation between their armed forces, including areas of military collaboration.

 

https://thecradle.co/articles/russia-afghanistan-sign-military-cooperation-deal-in-moscow

Anonymous ID: 3a4162 May 30, 2026, 11:51 a.m. No.24661160   🗄️.is 🔗kun   >>1322

Leftist German Party Leader Forced To Correct Lies About AfD Leader, Pay Her Legal Fees

 

When "blatant falsehoods are being spread, one cannot let them stand unchallenged," says Weidel's spokesman

 

Alice Weidel, co-leader of the anti-migration Alternative for Germany (AfD) party, has successfully sued the Left Party leader and won a retraction after she spread falsehoods about Weidel on live television.

 

In mid-May, Ines Schwerdtner, the federal chairwoman of the Left Party, claimed during an interview on Welt TV that Wediel neither resides in Germany nor pays taxes.

 

“Alice Weidel doesn’t even live in Germany, she doesn’t pay taxes here,” she told viewers. This statement is false. While Weidel spends much of her time with her family in Switzerland, she has her primary residence in Germany and pays taxes in the Federal Republic of Germany. Weidel has been very guarded about the issue over the years, as she faces a high threat level and avoids appearing in public due to the security threat she lives under.

 

Weidel’s lawyers explained in a warning letter, cited by Junge Freiheit, that this claim was false, as their client both lived in Germany and paid taxes.

 

The law firm Höcker filed a lawsuit on the AfD’s behalf seeking an injunction. Weidel’s lawyers also demanded that Schwerdtner ensure the relevant passage was deleted from Welt TV’s programming. Furthermore, the lawsuit calls on the Left Party leader to acknowledge the “claim for damages.”

 

Following this, Schwerdtner’s lawyer sent a letter to the Höcker law firm stating that their client had “indeed made a mistake.” The Left Party leader additionally undertook to “refrain” from making the false statement that Weidel does not pay taxes in Germany.

 

The letter also pointed out that the interview in question on Welt TV had since been deleted by the broadcaster. Furthermore, Schwerdtner stated that she would transfer the legal fees “within one week.”

 

Weidel’s press spokesman, Daniel Tapp, told JF that in politics one “shouldn’t be too sensitive in principle.” However, when “blatant falsehoods are being spread, one cannot let them stand unchallenged.”

 

The AfD has been surging in the polls, with one survey last week showing it hitting a record 42 percent in Saxony, double the support of the second-place Christian Democrats (CDU).

 

https://rmx.news/germany/germany-left-party-leader-forced-to-correct-lies-about-afd-leader-alice-weidel-pay-her-legal-fees/

Anonymous ID: 3a4162 May 30, 2026, 11:52 a.m. No.24661162   🗄️.is 🔗kun   >>1254 >>1351 >>1451 >>1619 >>1637 >>1670 >>1706

US will no longer bankroll wealthy NATO members – Hegseth

 

The US secretary of war has said America needs “partners, not protectorates,” amid a dispute over the military bloc’s burden sharing

 

The US will no longer “subsidize” the defense of “wealthy” allies, Secretary of War Pete Hegseth has said, reviving a long-running dispute between Washington and NATO’s European members over military spending.

 

The remarks were made at a major security summit in Singapore on Friday.

 

Hegseth linked the Trump administration’s push for higher allied defense spending to its broader strategy of shifting resources toward the Indo-Pacific and countering what he described as Chinese “hegemony” in the region.

 

“The era of the United States subsidizing the defense of wealthy nations is over. We need partners, not protectorates. We seek alliances built on shared responsibility, not dependency,” Hegseth told the annual International Institute for Strategic Studies Shangri-La Dialogue, according to an official statement by the Department of War.

 

NATO members agreed in 2014 to spend at least 2% of GDP on defense, but many EU countries failed to reach the target for years. Former President Barack Obama said in a 2016 interview that “free riders aggravate me,” calling on members to spend more.

 

According to NATO’s official figures, all 32 members met the 2% benchmark for the first time in 2025. However, the US still accounted for 60-62% of the bloc’s total military spending last year.

 

During a question-and-answer session following his address in Singapore, Hegseth described 2% contributions as “freeloading.”

 

Last year, NATO members agreed to work toward spending 5% of GDP on defense and security by 2035, including a core defense target of 3.5%.

 

Several governments have questioned the goal. Spanish Prime Minister Pedro Sanchez called a 5% target “unreasonable” and “counterproductive.” Belgium and Slovakia have also raised concerns over the scale of the increase.

 

The dispute has expanded beyond military spending as some EU governments have resisted Washington’s requests related to the Iran conflict. Spain has opposed the military action against Iran and refused to allow US forces to use joint bases for offensive operations, while France and Germany have called for diplomacy.

 

US President Donald Trump later criticized NATO allies over their response, saying it is “pretty shocking” that countries which support America’s objectives “don’t want to help.”

 

https://www.rt.com/news/640760-hegseth-eu-nato-military-contributions/

Anonymous ID: 3a4162 May 30, 2026, 11:56 a.m. No.24661172   🗄️.is 🔗kun   >>1389

Judge Refers Nigel Farage to Attorney General for Daring to Call Out ‘Two-Tier’ Justice.

 

A judge has referred comments made by Reform UK leader Nigel Farage to Britain’s Attorney General, accusing him of possible contempt of court.

 

Nigel Farage, leader of Britain’s Reform UK party, has been referred to Britain’s Attorney General, Labour politician Richard Hermer, after criticizing the country’s legal system. This follows the collapse of two trials for a Pakistani Muslim man accused of attacking police on video at Manchester Airport.

 

“It’s quite clear that our judiciary is in an even worse state than imagined. The politicisation of the courts ends under a Reform government.” – Nigel Farage

 

In July 2024, 20-year-old Mohammed Fahir Amaaz and 26-year-old Muhammad Amaad were arrested after police officers were attacked at Manchester Airport. There was a significant delay in bringing charges against the men, who initially claimed to be victims of police brutality. Farage criticized the delay in prosecution, stating: “[A] system of two-tier policing, under two-tier justice, under two-tier Keir [Starmer, the Prime Minister], has really taken hold. You only have to look at the reluctance to prosecute those violent thugs in Manchester Airport who beat up the police officers.”

 

Judge Neil Flewitt KC said, “I took the view that the observation made by Nigel Farage was potentially a contempt of court as it implied the guilt of the defendants… I decided to refer the matter to the Attorney General so that he could consider whether there should be a prosecution for contempt of court.” While convictions were secured for attacks on some of the officers involved, on Friday it was revealed that the two men would not face a third trial for attacks on one male officer, after two juries failed to reach verdicts. There has been widespread speculation that the juries remained deadlocked because some jurors were unwilling to convict members of their ethnic or religious community.

 

https://thenationalpulse.com/2026/05/29/judge-refers-nigel-farage-to-attorney-general-for-daring-to-call-out-two-tier-justice/

Anonymous ID: 3a4162 May 30, 2026, 12:05 p.m. No.24661192   🗄️.is 🔗kun

Trump Endorses Against GOP Congresswoman Who Defied Him On Epstein Files

 

President Donald Trump announced his support in South Carolina’s upcoming gubernatorial election for the opponent of a GOP lawmaker who broke with him over the release of the Jeffrey Epstein files.

 

The president wrote in a Friday post to Truth Social he is giving Republican South Carolina Lt. Gov. Pamela Evette his “Complete and Total Endorsement” in the crowded June 9 GOP primary for the state’s governorship, calling her “an America First Patriot who has been with me from the very beginning.” Evette is running against Republican South Carolina Rep. Nancy Mace, a firebrand lawmaker who was one of an initial four Republicans to defy Trump in the summer of 2025 in signing on to a Democrat-backed discharge petition to force the House to vote on the release of the unredacted Epstein files.

 

Evette “never wavered, never let me down, and was the only South Carolina Gubernatorial Candidate to Endorse me as soon as I launched my 2024 Presidential Campaign,” Trump wrote in his endorsement post, which does not mention Mace or any of Evette’s other primary opponents, such as Republican South Carolina Attorney General Alan Wilson. “She crisscrossed South Carolina and other States for me, and I said, at the time, that this is truly something which I cannot forget!”

 

In addition to her support of the Epstein discharge petition, Mace has spearheaded other efforts to bring Epstein’s sex crimes against children to the public light. In March, she led a House Oversight Committee effort to call then-Attorney General Pam Bondi to testify in front of Congress about her department’s release of the files.

 

“I have enormous respect for President Trump and everything he has done for our country and for South Carolina. That respect is genuine and it is unchanged,” Mace said in a statement following Trump’s endorsement of Evette.

 

“I also know I put the likelihood of an endorsement on the line when I demanded transparency on the Epstein files,” Mace continued. “I demanded it because you deserved the truth – ALL OF IT – and as a survivor, I had to get justice for these women. If this is the price of an endorsement, I will never pay it.”

 

Mace’s gubernatorial campaign referred the Daily Caller News Foundation to her statement when asked for comment.

 

In backing a challenger to Mace’s bid for higher office, the president has now either endorsed against or threatened to endorse against all four of the breakaway group of GOP lawmakers who signed onto the petition.

 

Trump successfully ousted the co-leader of the effort, Republican Kentucky Rep. Thomas Massie, in a May 19 primary which was the most expensive House nomination contest in U.S. history. Former Navy SEAL Ed Gallrein, who Trump endorsed before he entered the race, defeated Massie by a wider-than-expected margin of just under 10 points. In addition to the release of the files, the president and Massie had sparred over issues including the Iran war and the One, Big, Beautiful Bill Act.

 

Former Republican Georgia Rep. Marjorie Taylor Greene, who had also signed onto the petition, announced she was resigning from Congress in November 2025, one week after Trump withdrew his support of her and vowed to back a potential primary challenger. Trump in mid-May also threatened to back a primary challenger to Republican Colorado Rep. Lauren Boebert — another signatory of the Massie-led petition — after she campaigned for the Kentucky congressman against Gallrein.

 

In a November 2025 reversal of his previous stance vehemently opposing the petition, Trump called on House Republicans to release the Epstein files, quipping, “[W]e have nothing to hide, and it’s time to move on from this Democrat Hoax.” Days later, he signed the Epstein Files Transparency Act ordering the documents’ release, after it had passed Congress by a near-unanimous margin.

 

Hours before Trump issued his endorsement, Mace sent out an X post stating, “Pamela Evette is NOT ENDORSED by DONALD TRUMP. Do not believe her LIES.” The post remains live as of late Saturday morning.

 

https://dailycaller.com/2026/05/30/donald-trump-endorses-pamela-evette-south-carolina-governor-nancy-mace/

Anonymous ID: 3a4162 May 30, 2026, 12:14 p.m. No.24661208   🗄️.is 🔗kun   >>1269 >>1418

Iran Just Spit On Trump’s $300 Billion Bribe And Crypto Heist

 

Situation Room ran two full hours.

No decision.

Frozen funds still stuck.

Iran calls every Trump announcement pure wishes not reality. US just snatched another $1 billion straight from their crypto wallets and bragged about it live.

Tehran still demands the $12 billion unfrozen first and refuses one inch on nukes or Hormuz. Trump desperate for any win.

Iran not giving shit.

This farce is finished.

Real pain coming next week.

 

https://citizenwatchreport.com/iran-just-spit-on-trumps-300-billion-bribe-and-crypto-heist/

Anonymous ID: 3a4162 May 30, 2026, 12:18 p.m. No.24661214   🗄️.is 🔗kun

U.S. Attacked Another Ship Attempting To Reach Iran

 

The United States Central Command (CENTCOM) announced on May 30 that its forces in the Gulf of Oman enforced “blockade measures” by disabling a Gambia-flagged maritime vessel attempting to sail toward an Iranian port a day earlier.

 

In a statement, the command said that its forces observed the vessel, Lian Star, transiting international waters toward an Iranian port on the Gulf of Oman and issued more than 20 warnings while informing the vessel it was in violation of the U.S. blockade.

 

A U.S. aircraft disabled the vessel by firing a Hellfire missile into the ship’s engine room after Lian Star’s crew failed to comply, the command added, noting that the ship is no longer transiting to Iran.

 

According to CENTCOM, U.S. forces have disabled five commercial vessels and redirected 116 to fully enforce the blockade as a ceasefire with Iran remains in effect.

 

U.S. President Donald Trump ordered the blockade on Iranian ports on April 12, four days after the ceasefire went into effect, in response to the Islamic Republic’s restriction on maritime traffic in the Strait of Hormuz — a checkpoint for around 20 percent of global oil and liquefied natural gas shipments.

 

Iran has warned more than once in recent weeks that it would respond to such attacks by the U.S., and had hit back not just by attacking ships it deemed in violation of its measures in the waterway, but also by targeting U.S. warships. The Islamic Republic even renewed strikes on bases hosting U.S. forces in neighboring Gulf states.

 

In fact, the U.S. attack on Lian Star came just two days after an Iranian missile strike on Ali Al Salem Air Base in Kuwait, which hosts the 386th Air Expeditionary Wing of the U.S. Air Force. Five American contractors and active duty personnel were wounded, and two combat drones were hit, with at least one completely destroyed.

 

The escalation came as the Trump administration is reportedly weighing a possible agreement to extend the fragile ceasefire with Iran.

 

Trump held a roughly two-hour Situation Room meeting a day earlier but left without announcing a decision, despite hitting earlier that he was going to lift the blockade of Iranian ports.

 

https://southfront.press/u-s-attacked-another-ship-attempting-to-reach-iran/

Anonymous ID: 3a4162 May 30, 2026, 12:22 p.m. No.24661224   🗄️.is 🔗kun   >>1254 >>1351 >>1451 >>1619 >>1670 >>1706

Congress quietly moves to integrate US and Israeli militaries

 

In the first step towards shifting aid further into the shadows, the House’s 2027 NDAA would all but fuse the two countries’ armed forces together

At a time when the American public is expressing unprecedented levels of distrust in the Israeli government, Congress just proposed tying the U.S. to the Israeli military more than ever before.

 

Buried in the House’s version of the 2027 National Defense Authorization Act (NDAA) released on Tuesday, is section 224, entitled “United States-Israel Defense Technology Cooperation Initiative.” The provision would arguably do more to intertwine the U.S. military with the Israeli military than the more than $200 billion (inflation adjusted) in military assistance Israel has received from the U.S. since its founding in 1948.

 

Section 224 lays the groundwork for bilateral research and development, co-production of weapons, joint ventures, licensing agreements, and seemingly every manner of U.S.-Israeli military-industrial complex cooperation. The U.S. and Israel already work together heavily on missile defense, but this provision would greatly expand coordination to seemingly every area of defense tech, including AI, quantum, autonomous systems, directed energy, cyber, biotech, and many more. It also proposes “network integration” and “data fusion.” In other words, the U.S. military’s data could soon be the Israeli military’s data.

 

If fully enacted, this proposal would provide a higher level of military-industrial integration than the U.S. has with any other country in the world. To be sure, the U.S. has worked closely with its NATO partners on co-production and shared supply chains, most notably via the Defence Production Action Plan. And, as the number one arms dealer in the world, the U.S. provides weapons to militaries across the globe. But that is mostly a one-way street, with the U.S. providing weapons to foreign buyers who only occasionally make parts for those weapons themselves, as in the case of the F-35’s global supply chain.

 

Section 224 would be a different beast entirely. It would fuse the U.S. and Israeli defense sectors in multiple areas vital to the battlefields of the future, like autonomous systems and cyber. It would also bring extraordinary Israeli influence to the U.S. beyond what it already has through the Israel lobby and its robust network of social media influencers. It would give the Israeli government the opportunity to greatly expand one of the most powerful levers of influence in U.S. politics: jobs in the U.S. By expanding or starting new co-production facilities like it already has in Mississippi and Arkansas, the Israeli government could boast of providing jobs on U.S. soil, thereby securing allies among members of Congress who represent the districts where those jobs lie.

 

The result could well be a U.S. political system even more susceptible to the whims of an Israeli government that seemingly has no qualms about drawing the U.S. into military conflicts in the Middle East.

 

https://www.theburningplatform.com/2026/05/30/congress-quietly-moves-to-integrate-us-and-israeli-militaries/

Anonymous ID: 3a4162 May 30, 2026, 12:30 p.m. No.24661235   🗄️.is 🔗kun

Largest Human Cancer Study of Ivermectin and Mebendazole Is Now Peer-Reviewed and Published in a Major Cancer Journal

 

The largest real-world human study to date evaluating ivermectin and mebendazole in cancer patients is now peer-reviewed and published in Anticancer Research—a major international oncology journal of the International Institute of Anticancer Research (IIAR), established in 1995.

 

Our study, “Real-world Clinical Outcomes of Ivermectin and Mebendazole in Cancer Patients: Results from a Prospective Observational Cohort,” represents one of the most compelling clinical signals ever documented for repurposed anti-parasitic therapies in oncology.

 

Background/Aim: Drug repurposing offers a pathway to identify accessible, low-toxicity cancer therapies. Ivermectin and mebendazole demonstrate multi-target anticancer activity in preclinical models. This study evaluates real-world patient-reported outcomes, safety, and adherence in patients with cancer using this combination.

 

Patients and Methods: We analyzed a prospective observational cohort of 197 patients with cancer prescribed ivermectin and mebendazole off-label via a U.S. telemedicine platform. Participants received compounded capsules (25 mg ivermectin, 250 mg mebendazole). Data were collected through standardized digital surveys at baseline and 6-month follow-up. A total of 122 participants (61.9%) completed follow-up. Primary outcomes included self-reported cancer status, adherence, and adverse events. Confidence intervals were calculated using the Wilson method, with dose-stratified analyses using Chi-square tests.

 

Results: The cohort had a mean age of 67 years with balanced sex distribution and diverse malignancies, most commonly prostate (27.9%) and breast (18.3%). Median time since diagnosis was 1.2 years, with 37.1% reporting active progression at baseline. At six months, adherence was high, with 86.9% completing the initial prescription and 66.4% remaining on therapy. The Clinical Benefit Ratio (CBR) was 84.4% (95% confidence interval=77.0-89.8%). At follow-up, 48.4% of participants reported tumor regression or no evidence of disease (32.8% NED; 15.6% regression), while 36.1% reported stable disease and 15.6% reported progression. Side effects, reported by 25.4%, were dose-dependent and predominantly mild and primarily gastrointestinal, with 93.6% continuing therapy after adjustment. Concurrent therapies reported included chemotherapy (27.9%), radiation (21.3%), surgery (19.7%), supplements (49.2%), and dietary modification (37.7%).

 

Conclusion: In this prospective real-world cohort of patients with cancer, ivermectin and mebendazole were associated with high rates of self-reported clinical benefit and favorable tolerability. These findings are hypothesis-generating and support the need for randomized controlled trials.

 

https://ar.iiarjournals.org/content/46/6/3243