indeed, what isn't discussed is both psychoactive drugs, illicit or prescribed, and machine/software/gene interfacing with humans robs one of his or her identity.
both, save psychoactive drugs that actually benefit those 'temporarily' of disease, eventually disassociate the individual from who they would be normally (sober) psychoactive free, as it were, from artificial stimulus.
this is among the most tragic features of the residual effects of artificial stimulus to the individual, losing yourself.