Notable.
I've never heard of this one. It's anti parasite, like hydroxychloroquine and chloroquine.
Ivermectin
https://en.wikipedia.org/wiki/Ivermectin
Ivermectin was discovered in 1975 and came into medical use in 1981.[7][8] It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.[9] The wholesale cost in the developing world for the tablets is about US$0.12 for a course of treatment.[10] In the United States, the costs is less than US$50.[11][12] In other animals it is used to prevent and treat heartworm among other diseases.[3]
A couple days ago, we were looking at toxoplasma gondii (cat lady disease) and hydroxychloroquine. We saw that the Q drugs did treat cat lady disease.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116007/
In Vitro Effects of Ivermectin and Sulphadiazine on Toxoplasma gondii
These results indicate that ivermectin significantly inhibited replication of the tachyzoites of T. gondii RH strain.
Pubmed on Ivermectin
https://www.ncbi.nlm.nih.gov/pubmed/32135219
The broad spectrum antiviral ivermectin targets the host nuclear transport importin α/β1 heterodimer.
"Finally, we show for the first time that ivermectin can limit infection by the DENV-related West Nile virus at low (μM) concentrations. Since it is FDA approved for parasitic indications, ivermectin merits closer consideration as a broad spectrum antiviral of interest."
https://www.ncbi.nlm.nih.gov/pubmed/25730813
Evaluation of cytotoxicity and antiviral activity of ivermectin against Newcastle disease virus
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3888155/
Ivermectin is a potent inhibitor of flavivirus replication specifically targeting NS3 helicase activity: new prospects for an old drug
Conclusions
The well-tolerated drug ivermectin may hold great potential for treatment of YFV infections. Furthermore, structure-based optimization may result in analogues exerting potent activity against flaviviruses other than YFV.
https://www.biorxiv.org/content/10.1101/2020.03.20.999730v3
Identification of antiviral drug candidates against SARS-CoV-2 from FDA-approved drugs
We found a total of 24 drugs which exhibited antiviral efficacy (0.1 μM < IC50 < 10 μM) against SARS-CoV-2. In particular, two FDA-approved drugs - niclosamide and ciclesonide – were notable in some respects.
(((They))) want VACCINES. (((They))) don't want cures.
This one link - this came out about a week ago - shows a whole bunch of different things that kill C19
Look at the graphs. So many different drugs get up to 100% prevent pretty quickly. Chloroquine is there, but there are so many others.
I never want to hear in the future that there are no cures, when what the FDA really means is that no one spend a fuckton of money in order to do human trials on a NEW virus that is quite similar to an OLD virus.
https://www.biorxiv.org/content/10.1101/2020.03.20.999730v3.full
I think what baker should do, in terms of the notables on this one - would be about Ivermectin - and a bunch of the posts.