>>8885483
>AHHH DRRRRRR U NEED ZINC
Yes, I agree.
The idea of the use of zinc and Chloroquine/Hydroxychloroquine was presented by Dr. Seheult in the YouTube channel PubMed as follows:
Coronavirus Epidemic Update 34: US Cases Surge, Chloroquine & Zinc Treatment Combo, Italy Lockdown
https://www.youtube.com/watch?v=U7F1cnWup9M&t=943s
A possible mechanism is also discussed. The point is that Chloroquine/Hydroxychloroquine works as a zinc ionophore.
In another video he discusses other possible ionophores, quercetin and epigallocatechin-gallate. Therefore, it is interesting to see the effect of the dose of both zinc and quercetin/epigallocatechin-gallate.
Coronavirus Pandemic Update 35: New Outbreaks & Travel Restrictions, Possible COVID-19 Treatments
https://www.youtube.com/watch?v=vE4_LsftNKM
"Xue J, Moyer A, Peng B, Wu J, Hannafon BN, Ding W-Q (2014)
Chloroquine Is a Zinc Ionophore
PLoS ONE 9(10): e109180. https://doi.org/10.1371/journal.pone.0109180" which was supported in part by the NIH, please, be aware that this work was done in vitro. The results shown in this publication of Xue J et al. provide pretty much evidence for the combined use of chloroquine/hydroxychloroquine in COVID-19 treatment strategies. However, to our knowledge, no controlled clinical study with chloroquine/hydroxychloroquine combined with zinc supplementation has been published in the context of COVID-19 therapy.
Does Zinc Supplementation Enhance the Clinical Efficacy of Chloroquine/Hydroxychloroquine to Win Todays Battle Against COVID-19?
https://www.preprints.org/manuscript/202004.0124/v1
The authors are correct - there are now 3 registered clinical trials which involve both CQ/HCQ and Zn(II) - two of them look at prevention, and one - at treatment. Results will be available in 24 weeks.
To the best of my knowledge, there is no literature data which links the two with Covid-19 - the paper you mention by Xue et at. is the base of the theory, yes, but it shows exactly what it says in the title (Chloroquine Is a Zinc Ionophore) and does not link CQ to any viral infection.