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9) Alicia Rodríguez-Gascón, Ana del Pozo-Rodríguez, and María Ángeles Solinís, Development of nucleic acid vaccines: use of self-amplifying RNA in lipid nanoparticles Int J Nanomedicine. 2014; 9: 1833–1843. Published online 2014 Apr 10. doi: 10.2147/IJN.S39810 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986288/ (In Europe, all mRNA-based therapies fall under the scope of the regulation for advanced therapy medicinal products.27,28 “In Europe, all mRNA-based therapies fall under the scope of the regulation for advanced therapy medicinal products.27,28 gene therapy medicinal product is an active substance which contains or consists of a recombinant nucleic acid used in or administered to human beings”; therefore, mRNA is categorized as gene therapy. In contrast, in the USA, mRNA-based vaccination therapies are not considered as gene therapy.”)
10) Kreiter S, Diken M, Selmi A, Türeci Ö, Sahin U., Tumor vaccination using messenger RNA: prospects of a future therapy, Curr Opin Immunol. 2011 Jun;23(3):399-406. doi: 10.1016/j.coi.2011.03.007. Epub 2011 Apr 13., https://www.ncbi.nlm.nih.gov/pubmed/21497074
11) Yanez Arteta M, Kjellman T, Bartesaghi S, Wallin S, Wu X, Kvist AJ, Dabkowska A, Székely N, Radulescu A, Bergenholtz J, Lindfors L. Successful reprogramming of cellular protein production through mRNA delivered by functionalized lipid nanoparticles. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3351-E3360. doi: 10.1073/pnas.1720542115. Epub 2018 Mar 27. https://www.ncbi.nlm.nih.gov/pubmed/29588418
12) Andreas Thess, Stefanie Grund, Barbara L Mui, Michael J Hope, Patrick Baumhof, Mariola Fotin-Mleczek, and Thomas Schlake, Sequence-engineered mRNA Without Chemical Nucleoside Modifications Enables an Effective Protein Therapy in Large Animals, Mol Ther. 2015 Sep; 23(9): 1456–1464. Published online 2015 Jun 30. Prepublished online 2015 Jun 8. doi: 10.1038/mt.2015.103 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4817881/
13) World Health Organization, Bulletin of the World Health Organization, 2001,79(12), https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566717/pdf/11799456.pdf
14) Zeljka Trepotec, Eva Lichtenegger, Christian Plank, Manish K. Aneja, Carsten Rudolph, Delivery of mRNA Therapeutics for the Treatment of Hepatic Diseases. Review| Volume 27, ISSUE 4, p 794-802, April 10, 2019 https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(18)30616-6
15) Xiangjun Tang, Shenqi Zhang, Rui Fu, Li Zhang, Kuanming Huang, Hao Peng, Longjun Dai, and Qianxue Chen, Therapeutic Prospects of mRNA-Based Gene Therapy for Glioblastoma, Front Oncol. 2019; 9: 1208. Published online 2019 Nov 8. doi: 10.3389/fonc.2019.01208 , https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857656/#B25
16) Annette B.Vogel, LauraLambert, EkaterinaKinnear, DavidBusse, StephanieErbar, Kerstin C.Reuter, LenaWicke, MarioPerkovic, TimBeissert, HeinrichHaas, Stephen T.Reece, UgurSahin, John S.Tregoning, Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses, Molecular Therapy , Volume 26, Issue 2, 7 February 2018, Pages 446-455, https://doi.org/10.1016/j.ymthe.2017.11.017 , https://www.sciencedirect.com/science/article/pii/S1525001617305944
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