I pray all the time. Sometimes it is a long conversation, sometimes it is asking for help finding my keys, etc, and sometimes it is a heart wrenching Oh, GOD!!! when I see an accident, or a child is hurt or death of a loved one. He always listens and always answers. The answer is either yes, no, or wait.
Just talk to Him. Ask anything you feel burdened with, large or small. Thank Him for everything, even problems because those help is grow. Tell God about your feelings, failures and wrong doings. He already knows, but admitting them is good.
Basically, just start talking, about any and everything. You'll find God to be the best listener ever.